2022

2022

• Association between tissue hypoxia, perfusion restrictions, and microvascular architecture alterations with lesion-induced impairment of neurovascular coupling.
  Stadlbauer A, Kinfe TM, Zimmermann M, Eyüpoglu I, Brandner N, Buchfelder M, Zaiss M, Dörfler A, Brandner S.
  J Cereb Blood Flow Metab. 2022 Mar;42(3):526-539.
• 131I-GD2-ch14.18 Scintigraphy to Evaluate Option for Radioimmunotherapy in Patients with Advanced Tumors.
  Zhang Y, Kupferschlaeger J, Lang P, Reischl G, Handgretinger RJ, Fougère C, Dittmann H.
  J Nucl Med. 2022 Feb;63(2):205-211.
• Two experts and a newbie: [18F]PARPi vs [18F]FTT vs [18F]FPyPARP-a comparison of PARP imaging agents.
  Stotz S, Kinzler J, Nies AT, Schwab M, Maurer A.
  Eur J Nucl Med Mol Imaging. 2022 Feb;49(3):834-846.
• Physiological MRI of microvascular architecture, neovascularization activity, and oxygen metabolism facilitate early recurrence detection in patients with IDH-mutant WHO grade 3 glioma.
  Stadlbauer A, Heinz G, Oberndorfer S, Zimmermann M, Kinfe TM, Buchfelder M, Dörfler A, Kremenevski N, Marhold F.
  Neuroradiology. 2022 Feb;64(2):265-277.
• Tissue metabolites in diffuse glioma and their modulations by IDH1 mutation, histology, and treatment.
  Trautwein C, Zizmare L, Mäurer I, Bender B, Bayer B, Ernemann U, Tatagiba M, Grau SJ, Pichler BJ, Skardelly M, Tabatabai G.
  JCI Insight. 2022 Feb 8;7(3):e153526.
• Impact of 18F-FET PET/MRI on Clinical Management of Brain Tumor Patients.
  Brendle C, Maier C, Bender B, Schittenhelm J, Paulsen F, Renovanz M, Roder C, Castaneda-Vega S, Tabatabai G, Ernemann U, Fougère C.
  J Nucl Med. 2022 Apr;63(4):522-527.
• Thyroid Metastasis in Whole-Body 18F-FDG PET/CT Restaging of Small Cell Lung Cancer.
  Vogel J, Tenev A, Solass W, Schwenck J, Dittmann H.
  Clin Nucl Med. 2022 Jan 1;47(1):96-97.
• NEMA NU 4-2008 performance evaluation and MR compatibility tests of an APD-based small animal PET-insert for simultaneous PET/MR imaging.
  Disselhorst JA, Newport DF, Schmid AM, Schmidt FP, Parl C, Liu CC, Pichler BJ, Mannheim JG.
  Phys Med Biol. 2022 Feb 16;67(4).
• Editorial to the Special Issue Entitled "Imaging in Immunooncology".
  Fruhwirth GO, Weigelin B, Daldrup-Link HE, Ponomarev V.
  Mol Imaging Biol. 2022 Apr;24(2):177-180.
• Intratumoral in vivo staging of breast cancer by multi-tracer PET and advanced analysis.
  Griessinger J, Schwab J, Chen Q, Kühn A, Cotton J, Bowden G, Preibsch H, Reischl G, Quintanilla-Martinez L, Mori H, Dang AN, Kohlhofer U, Aina OH, Borowsky AD, Pichler BJ, Cardiff RD, Schmid AM.
  NPJ Breast Cancer. 2022 Mar 24;8(1):41.
• Quantitative Metabolomics of Tissue, Perfusate, and Bile from Rat Livers Subjected to Normothermic Machine Perfusion.
  Lonati C, Dondossola D, Zizmare L, Battistin M, Wüst L, Vivona L, Carbonaro M, Zanella A, Gatti S, Schlegel A, Trautwein C.
  Biomedicines. 2022 Feb 24;10(3):538.
• Roux-En-Y Gastric Bypass (RYGB) Surgery during High Liquid Sucrose Diet Leads to Gut Microbiota-Related Systematic Alterations.
  Zizmare L, Boyle CN, Buss S, Louis S, Kuebler L, Mulay K, Krüger R, Steinhauer L, Mack I, Rodriguez Gomez M, Herfert K, Ritze Y, Trautwein C.
  Int J Mol Sci. 2022 Jan 20;23(3):1126.
• Imaging the Rewired Metabolism in Lung Cancer in Relation to Immune Therapy.
  van Genugten EAJ, Weijers JAM, Heskamp S, Kneilling M, van den Heuvel MM, Piet B, Bussink J, Hendriks LEL, Aarntzen EHJG.
  Front Oncol. 2022 Jan 7;11:786089.
• CD147 a direct target of miR-146a supports energy metabolism and promotes tumor growth in ALK+ ALCL.
  Montes-Mojarro IA, Steinhilber J, Griessinger CM, Rau A, Gersmann AK, Kohlhofer U, Fallier-Becker P, Liang HC, Hofmann U, Haag M, Klapper W, Schaeffeler E, Pichler BJ, Schwab M, Fend F, Bonzheim I, Quintanilla-Martinez L.
  Leukemia. 2022 Jun 8.
• Dose escalation to hypoxic subvolumes in head and neck cancer: A randomized phase II study using dynamic [18F]FMISO PET/CT.
  Welz S, Paulsen F, Pfannenberg C, Reimold M, Reischl G, Nikolaou K, La Fougère C, Alber M, Belka C, Zips D, Thorwarth D.
  Radiother Oncol. 2022 Jun;171:30-36.
• Antibody-guided Molecular Imaging of Aspergillus Lung Infections in Leukemia Patients
  Schwenck J, Maurer A, Beziere N, Fiz F, Boschetti F, Geistlich S, Seyfried D, Gunzer M, Reischl G, Wehrmüller J, Ehrlichmann W, Horger M, Gatidis S, Davies G, Vogel W, la Fougere C, Pichler BJ, Thornton C
  J Nucl Med. 2022 Jul 21:jnumed.121.263251
• Translational immunoPET imaging using a radiolabeled GD2-specific antibody in neuroblastoma
  Schmitt J, Schwenck J, Maurer A, Przybille M, Sonanini D, Reischl G, Wehrmuller JE, Quintanilla-Martinez L, Gillies SD, Krueger MA, Schaefer JF, la Fougere C, Handgretinger R, Pichler BJ
  Theranostics, 12 (12) , pp.5615-5630
• Using micro-synchrotron radiation x-ray fluorescence (µ-SRXRF) for trace metal imaging in the development of MRI contrast agents for prostate cancer imaging
  Dao E, Clavijo Jordan MV, Geraki K, Martins AF, Chirayil S, Sherry AD, Farquharson MJ
  J Trace Elem Med Biol. 2022 Dec;74:127054
• T cell-mediated additive cytotoxicity - death by multiple bullets
  Weigelin B, Friedl P
  Trends Cancer. 2022 Dec;8(12):980-987
• Identification of neurodegeneration indicators and disease progression in metachromatic leukodystrophy using quantitative NMR-based urinary metabolomics
  Laugwitz L, Zizmare L, Santhanakumaran V, Cannet C, Böhringer J, Okun JG, Spraul M, Krägeloh-Mann I, Groeschel S, Trautwein C
  JIMD Rep. 2022 Jan 27;63(2):168-180
• A role for artificial intelligence in molecular imaging of infection and inflammation
  Schwenck J, Kneilling M, Riksen NP, la Fougère C, Mulder DJ, Slart RJHA, Aarntzen EHJG
  Eur J Hybrid Imaging. 2022 Sep 1;6(1):17
• Combining CRISPR-Cas9 and brain imaging to study the link from genes to molecules to networks
  Marciano S, Ionescu TM, Saw RS, Cheong RY, Kirik D, Maurer A, Pichler BJ, Herfert K
  Proc Natl Acad Sci U S A. 2022 Oct 4;119(40)
• Understanding the importance of quality control and quality assurance in preclinical PET/CT imaging
  McDougald WA, Mannheim JG
  EJNMMI Phys. 2022 Oct 31;9(1):77
• Acute and chronic inflammation alter immunometabolism in a cutaneous delayed-type hypersensitivity reaction (DTHR) mouse model
  Zizmare L, Mehling R, Gonzalez-Menendez I, Lonati C, Quintanilla-Martinez L, Pichler BJ, Kneilling M, Trautwein C.
  Commun Biol. 2022 Nov 15;5(1):1250
• Multiparametric Longitudinal Profiling of RCAS-tva-Induced PDGFB-Driven Experimental Glioma
  Becker H, Castaneda-Vega S, Patzwaldt K, Przystal JM, Walter B, Michelotti FC, Canjuga D, Tatagiba M, Pichler B, Beck SC, Holland EC, la Fougère C, Tabatabai G
  Brain Sci. 2022 Oct 24;12(11):1426
• Spatiotemporal patterns of putaminal dopamine processing in Parkinson's disease: A multi-tracer positron emission tomography study
  Fu JF, Wegener T, Klyuzhin IS, Mannheim JG, McKeown MJ, Stoessl AJ, Sossi V
  Neuroimage Clin. 2022;36:103246
• The Current Role of Peptide Receptor Radionuclide Therapy in Meningiomas
  Fodi CK, Schittenhelm J, Honegger J, Castaneda-Vega SG, Behling F
  J Clin Med. 2022 Apr 23;11(9):2364
• Image quality assessment along the one metre axial field-of-view of the total-body Biograph Vision Quadra PET/CT system for 18F-FDG
  Rausch I, Mannheim JG, Kupferschläger J, la Fougère C, Schmidt FP
  EJNMMI Phys. 2022 Dec 14;9(1):87
• Adenosine A2a Receptor Antagonism Restores Additive Cytotoxicity by Cytotoxic T Cells in Metabolically Perturbed Tumors
  Slaats J, Wagena E, Smits D, Berends AA, Peters E, Bakker GJ, van Erp M, Weigelin B, Adema GJ, Friedl P
  Cancer Immunol Res. 2022 Dec 2;10(12):1462-1474
• Quantitative Serum NMR Spectroscopy Stratifies COVID-19 Patients and Sheds Light on Interfaces of Host Metabolism and the Immune Response with Cytokines and Clinical Parameters
  Rössler T, Berezhnoy G, Singh Y, Cannet C, Reinsperger T, Schäfer H, Spraul M, Kneilling M, Merle U, Trautwein C
  Metabolites. 2022 Dec 16;12(12):1277
• Acidic ascites inhibits ovarian cancer cell proliferation and correlates with the metabolomic, lipidomic and inflammatory phenotype of human patients
  Yang Q, Bae G, Nadiradze G, Castagna A, Berezhnoy G, Zizmare L, Kulkarni A, Singh Y, Weinreich FJ, Kommoss S, Reymond MA, Trautwein C
  Transl Med. 2022 Dec 12;20(1):581
• Quantitative NMR-Based Lipoprotein Analysis Identifies Elevated HDL-4 and Triglycerides in the Serum of Alzheimer's Disease Patients
  Berezhnoy G, Laske C, Trautwein C
  Int J Mol Sci. 2022 Oct 18;23(20):12472
• Practical considerations for navigating the regulatory landscape of non-clinical studies for clinical translation of radiopharmaceuticals
  Korde A, Mikolajczak R, Kolenc P, Bouziotis P, Westin H, Lauritzen M, Koole M, Herth MM, Bardiès M, Martins AF, Paulo A, Lyashchenko SK, Todde S, Nag S, Lamprou E, Abrunhosa A, Giammarile F, Decristoforo C
  EJNMMI Radiopharm Chem. 2022 Jul 19;7(1):18
• Mesaconate is synthesized from itaconate and exerts immunomodulatory effects in macrophages
  He W, Henne A, Lauterbach M, Geißmar E, ... , Heinz A, Dostert C, Grusdat M, Cordes T, Härm J, Goldmann O, Ewen A, Verschueren C, Blay-Cadanet J, Geffers R, Garritsen H, Kneiling M, Holm CK, Metallo CM, Medina E, Abdullah Z, Latz E, Brenner D, Hiller K
  Nat Metab. 2022 May;4(5):524-533
• Brain sex-dependent alterations after prolonged high fat diet exposure in mice
  Murtaj V, Penati S, Belloli S, Foti M, Coliva A, Papagna A, Gotti C, Toninelli E, Chiaffarelli R, Mantero S, Pucci S, Matteoli M, Malosio ML, Moresco RM
  Commun Biol. 2022 Nov 21;5(1):1276
• The OpenGATE ecosystem for Monte Carlo simulation in medical physics
  Sarrut D, Arbor N, Baudier T, Borys D, Etxebeste A, Fuchs H, Gajewski J, Grevillot L, Jan S, Kagadis GC, Kang HG, Kirov A, Kochebina O, Krzemien W, Lomax A, Papadimitroulas P, Pommranz C, Roncali E, Rucinski A, Winterhalter C, Maigne L
  Phys Med Biol. 2022 Sep 8;67(18)
• The Oncolytic Adenovirus XVir-N-31, in Combination with the Blockade of the PD-1/PD-L1 Axis, Conveys Abscopal Effects in a Humanized Glioblastoma Mouse Model
  Klawitter M, El-Ayoubi A, Buch J, Rüttinger J, Ehrenfeld M, Lichtenegger E, Krüger MA, Mantwill K, Koll FJ, Kowarik MC, Holm PS, Naumann U
  Int J Mol Sci. 2022 Sep 1;23(17):9965
• Patient-individual phenotypes of glioblastoma stem cells are conserved in culture and associate with radioresistance, brain infiltration and patient prognosis
  Ganser K, Eckert F, Riedel A, Stransky N, Paulsen F, Noell S, Krueger M, Schittenhelm J, Beck-Wödl S, Zips D, Ruth P, Huber SM, Klumpp L
  Int J Cancer. 2022 May 15;150(10):1722-1733
• Data on common carotid artery occlusion inducing focalized stroke lesions after Pertussis toxin injection
  Leiss V, Piekorz RP, Vega SC, Jacoby C, Flögel U, Pexa K, Schrader J, Pichler BJ, Beer-Hammer S, Nürnberg B
  Data Brief. 2022 Dec 25;46:108851