Immunomodulatory role of reactive oxygen species and nitrogen species during T cell-driven neutrophil-enriched acute and chronic cutaneous delayed-type hypersensitivity reactions Mehling R, Schwenck J, Lemberg C, Trautwein C, Zizmare L, Kramer D, Müller A, Fehrenbacher B, Gonzalez-Menendez I, Quintanilla-Martinez L, Schröder K, Brandes RP, Schaller M, Ruf W, Eichner M, Ghoreschi K, Röcken M, Pichler BJ, Kneilling M Theranostics. 2021 Jan 1;11(2):470-490 Rapid and precise delivery of cells in the urethral sphincter complex by a novel needle-free waterjet technology Linzenbold W, Jäger L, Stoll H, Abruzzese T, Harland N, Bézière N, Fech A, Enderle M, Amend B, Stenzl A, Aicher WK BJU Int. 2021 Apr;127(4):463-472 Noninvasive, longitudinal imaging-based analysis of body adipose tissue and water composition in a melanoma mouse model and in immune checkpoint inhibitor-treated metastatic melanoma patients Thaiss WM, Gatidis S, Sartorius T, Machann J, Peter A, Eigentler TK, Nikolaou K, Pichler BJ, Kneilling M Cancer Immunol Immunother. 2021 May;70(5):1263-1275 [11C]MODAG-001-towards a PET tracer targeting α-synuclein aggregates Kuebler L, Buss S, Leonov A, Ryazanov S, Schmidt F, Maurer A, Weckbecker D, Landau AM, Lillethorup TP, Bleher D, Saw RS, Pichler BJ, Griesinger C, Giese A, Herfert K Eur J Nucl Med Mol Imaging. 2021 Jun;48(6):1759-1772 Non invasive in vivo monitoring of dimethyl fumarate treatment in EAE by assessing the glucose metabolism in secondary lymphoid organs Brück J, Calaminus C, Hoffmann SHL, Schwenck J, Holstein J, Yazdi AS, Pichler B, Kneilling M, Ghoreschi K Eur J Immunol. 2021 Apr;51(4):1006-1009 An IgG-based bispecific antibody for improved dual targeting in PSMA-positive cancer Zekri L, Vogt F, Osburg L, Müller S, Kauer J, Manz T, Pflügler M, Maurer A, Heitmann JS, Hagelstein I, Märklin M, Hörner S, Todenhöfer T, Calaminus C, Stenzl A, Pichler B, la Fougère C, Schneider MA, Rammensee HG, Zender L, Sipos B, Salih HR, Jung G EMBO Mol Med. 2021 Feb 5;13(2):e11902 Machine learning identifies stroke features between species Castaneda-Vega S, Katiyar P, Russo F, Patzwaldt K, Schnabel L, Mathes S, Hempel JM, Kohlhofer U, Gonzalez-Menendez I, Quintanilla-Martinez L, Ziemann U, la Fougere C, Ernemann U, Pichler BJ, Disselhorst JA, Poli S Theranostics. 2021 Jan 1;11(6):3017-3034. doi: 10.7150/thno.51887 Manganese(II)-Based Responsive Contrast Agent Detects Glucose-Stimulated Zinc Secretion from the Mouse Pancreas and Prostate by MRI Chirayil S, Jordan VC, Martins AF, Paranawithana N, Ratnakar SJ, Sherry AD Inorg Chem. 2021 Jan 28. doi: 10.1021/acs.inorgchem.0c02688. Epub ahead of print Tissue Hypoxia and Alterations in Microvascular Architecture Predict Glioblastoma Recurrence in Humans Stadlbauer A, Kinfe TM, Eyüpoglu I, Zimmermann M, Kitzwögerer M, Podar K, Buchfelder M, Heinz G, Oberndorfer S, Marhold F Clin Cancer Res. 2021 Mar 15;27(6):1641-1649 A T 2ex MRI Dy-based contrast agent for direct pH imaging using a ratiometric approach Zhang Y , Zhao K , He H , Wan S , Martins AF , Zhang L , Liu K Dalton Trans. 2021 Feb 14;50(6):2014-2017 Cross-validation study between the HRRT and the PET component of the SIGNA PET/MRI system with focus on neuroimaging Mannheim JG, Cheng JK, Vafai N, Shahinfard E, English C, McKenzie J, Zhang J, Barlow L, Sossi V EJNMMI Phys. 2021 Feb 26;8(1):20 A single pot template reaction towards a manganese based T1 contrast agent. Anbu S, Hoffmann SHL, Carniato F, Kenning L, Price TW, Prior TJ, Botta M, Martins AF, Stasiuk GJ Angew Chem Int Ed Engl. 2021 Feb 24. doi: 10.1002/anie.202100885. Epub ahead of print. Antibody-guided in vivo imaging of Aspergillus fumigatus lung infections during antifungal azole treatment Henneberg S, Hasenberg A, Maurer A, Neumann F, Bornemann L, Gonzalez-Menendez I, Kraus A, Hasenberg M, Thornton CR, Pichler BJ, Gunzer M, Beziere N Nat Commun. 2021 Mar 17;12(1):1707 Elucidating the complementarity of resting-state networks derived from dynamic [ 18 F]FDG and hemodynamic fluctuations using simultaneous small-animal PET/MRI Ionescu TM, Amend M, Hafiz R, Biswal BB, Wehrl HF, Herfert K, Pichler BJ Neuroimage. 2021 Apr 10;236:118045 [18F]fluoro-ethylcholine-PET Plus 4D-CT (FEC-PET-CT): A Break-Through Tool to Localize the "Negative" Parathyroid Adenoma. One Year Follow Up Results Involving 170 Patients. Smaxwil C, Aschoff P, Reischl G, Busch M, Wagner J, Altmeier J, Ploner O, Zielke A J Clin Med. 2021 Apr 13;10(8):1648. doi: 10.3390/jcm10081648 The C5a/C5a receptor 1 axis controls tissue neovascularization through CXCL4 release from platelets Nording H, Baron L, Haberthür D, ... , Feil R, Pichler B, Erdmann J, ... , Gawaz M, Langer HF Nat Commun. 2021 Jun 7;12(1):3352 Metabolic Screening of Cytotoxic T-cell Effector Function Reveals the Role of CRAC Channels in Regulating Lethal Hit Delivery Slaats J, Dieteren CE, Wagena E, Wolf L, Raaijmakers TK, van der Laak JA, Figdor CG, Weigelin B, Friedl P Cancer Immunol Res. 2021 Jul 5 Mathematical Modelling Based on In Vivo Imaging Suggests CD137-Stimulated Cytotoxic T Lymphocytes Exert Superior Tumour Control Due to an Enhanced Antimitotic Effect on Tumour Cells Beck RJ, Weigelin B, Beltman JB Cancers (Basel). 2021 May 24;13(11):2567 131Iodine-GD2-ch14.18 scintigraphy to evaluate option for radioimmunotherapy in patients with advanced tumors Zhang Y, Kupferschlaeger J, Lang P, Reischl G, Handgretinger R, la Fougere C, Dittmann H J Nucl Med. 2021 May 28:jnumed.120.261854 Central insulin modulates dopamine signaling in the human striatum Kullmann S, Blum D, Jaghutriz BA, Gassenmaier C, Bender B, Häring HU, Reischl G, Preissl H, la Fougère C, Fritsche A, Reimold M, Heni M J Clin Endocrinol Metab. 2021 Jun 15:dgab410 Advancing Biomarker Development Through Convergent Engagement: Summary Report of the 2nd International Danube Symposium on Biomarker Development, Molecular Imaging and Applied Diagnostics; March 14-16, 2018; Vienna, Austria. Lim MS, Beyer T, Babayan A, Bergmann M, ..., Mitterhauser M, Pichler BJ, Salih HR, Schibli R, Schulz S, Simecek J, Simon J, Soares MO, Stelzl U, Wadsak W, Zatloukal K, Zeitlinger M, Hacker M Mol Imaging Biol. 2020 Feb; 22(1):47-65 Imaging SERT Availability in a Rat Model of L-DOPA-Induced Dyskinesia. Walker M, Kuebler L, Goehring CM, Pichler BJ, Herfert K Mol Imaging Biol. 2020 Jun;22(3):634-642. Temporal Dynamics of Reactive Oxygen and Nitrogen Species and NF-κB Activation During Acute and Chronic T Cell-Driven Inflammation. Schwenck J, Mehling R, Thaiss WM, Kramer D, Menendez IG, Öz HH, Hartl D, Schulze-Osthoff K, Hailfinger S, Ghoreschi K, Quintanilla-Martinez L, Carlsen H, Röcken M, Pichler BJ, Kneilling M Mol Imaging Biol. 2020 Jun;22(3):504-514. PET/MRI enables simultaneous in vivo quantification of β-cell mass and function. Michelotti FC, Bowden G, Küppers A, Joosten L, Maczewsky J, Nischwitz V, Drews G, Maurer A, Gotthardt M, Schmid AM, Pichler BJ Theranostics 2020 Jan; 10(1):398-410. Cancer immunotherapy is accompanied by distinct metabolic patterns in primary and secondary lymphoid organs observed by non-invasive in vivo 18F-FDG-PET. Schwenck J, Schörg B, Fiz F, Sonanini D, Forschner A, Eigentler T, Weide B, Martella M, Gonzalez-Menendez I, Campi C, Sambuceti G, Seith F, Quintanilla-Martinez L, Garbe C, Pfannenberg C, Röcken M, Fougere Cl, Pichler BJ, Kneilling M Theranostics 2020 Jan; 10(2):925-937. Selective protection of murine cerebral G(i/o)-proteins from inactivation by parenterally injected pertussis toxin. Vega SC, Leiss V, Piekorz R, Calaminus C, Pexa K, Vuozzo M, Schmid AM, Devanathan V, Kesenheimer C, Pichler BJ, Beer-Hammer S, Nürnberg B J Mol Med 2020 Jan; 98(1): 97-110 Simultaneous whole-body PET/MRI with integrated multiparametric MRI for primary staging of high-risk prostate cancer. Kaufmann S, Kruck S, Gatidis S, Hepp T, Thaiss WM, Hennenlotter J, Schwenck J, Scharpf M, Nikolaou K, Stenzl A, Reischl G, la Fougère C, Bedke J World J Urol. 2020 Jan; [Epub ahead of print] Circadian rhythm impacts preclinical FDG-PET quantification in the brain, but not in xenograft tumors. Krueger MA, Calaminus C, Schmitt J, Pichler BJ Sci Rep. 2020 Mar; 10(1): 5587 Cancer immune control needs senescence induction by interferon-dependent cell cycle regulator pathways in tumours. Brenner E, Schörg BF, Ahmetlić F, Wieder T, Hilke FJ, Simon N, Schroeder C, ... ,Quintanilla-Martinez L, Pichler BJ, Kneilling M, Mocikat R, Röcken M Nat Commun. 2020 Mar; 11(1): 1335 11 C Radiolabeling of anle253b: a Putative PET Tracer for Parkinson's Disease That Binds to α-Synuclein Fibrils in vitro and Crosses the Blood-Brain Barrier. Maurer A, Leonov A, Ryazanov S, Herfert K, Kuebler L, Buss S, Schmidt F, Weckbecker D, Linder R, Bender D, Giese A, Pichler BJ, Griesinger C ChemMedChem. 2020 Mar; 15(5): 411-415 The scaffold protein p62 regulates adaptive thermogenesis through ATF2 nuclear target activation. Fischer K, Fenzl A, Liu D, ..., Brüning JC, Kneilling M, Maier FC, Othman AE, Pichler BJ, Pramme-Steinwachs I, Sachs S, Scheideler A, Thaiss WM, Uhlenhaut H, Ussar S, Woods SC, Zorn J, Stemmer K, Collins S, Diaz-Meco M, Moscat J, Tschöp MH, Müller TD Nat Commun. 2020 May 8; 11(1):2306. doi: 10.1038/s41467-020-16230-8. Extensive rewiring of the EGFR network in colorectal cancer cells expressing transforming levels of KRASG13D. Kennedy SA, Jarboui MA, Srihari S, Raso C, Bryan K, Dernayka L, Charitou T, Bernal-Llinares M, Herrera-Montavez C, Krstic A, ... Auer M, Horn N, Klose F, Ueffing M, Boldt K, Lynn DJ, Kolch W Nat Commun. 2020 Jan 24;11(1):499. doi: 10.1038/s41467-019-14224-9. Lactate production precedes inflammatory cell recruitment in arthritic ankles: an imaging study Neveu MA, Beziere N, Daniels R, Bouzin C, Comment A, Schwenck J, Fuchs K, Kneilling M, Pichler BJ, Schmid AM Mol Imaging Biol. 2020 Jun 8. doi: 10.1007/s11307-020-01510-y. Online ahead of print. Correlated Multimodal Imaging in Life Sciences: Expanding the Biomedical Horizon Walter A, Paul-Gilloteaux P, Plochberger B, Sefc L, Verkade P, Mannheim JG, Slezak P, Unterhuber A, Marchetti-Deschmann M, Ogris M, Bühler K, Fixler D, Geyer SH, Weninger WJ, Glösmann M, Handschuh S, Wanek T Front. Phys., 09 April 2020 https://doi.org/10.3389/fphy.2020.00047 Modulating endothelial adhesion and migration impacts stem cell therapies efficacy Schäfer R, Schwab M,Siegel G, von Ameln-Mayerhofer A, Buadzec M, Lourhmati A, Wendel H-P, Kluba T, Krueger, M A, Calaminus C, Scheer E, ... Claussen C D, Seifried E, Hermann D M, Northoff H, Danielyan L EBioMedicine, Volume 60, 2020, 102987 DJ-1 (Park7) affects the gut microbiome, metabolites and the development of innate lymphoid cells (ILCs) Singh Y, Trautwein C, Dhariwal A, Salker MS, Alauddin Md, Zizmare L, Pelzl L, Feger M, Admard J, Casadei N, Föller M, Pachauri V, Park DS, Mak TW, Frick J-S, Wallwiener D, Brucker SY, Lang F, Riess O Sci Rep . 2020 Sep 30;10(1):16131 Cell motility and migration as determinants of stem cell efficacy Danielyan L, Schwab M, Siegel G, ... , Krueger MA, Calaminus C, Naumann U, Winter S, Schaeffeler E, Spogis A, Beer-Hammer S, ... , Hermann DM, Doeppner TR, Seifried E, Gleiter CH, Northoff H, Schäfer R. EBioMedicine. 2020 Sep 10;60:102989. Online ahead of print. Quo Vadis, Molecular Imaging? Grimm J, Kiessling F, Pichler BJ J Nucl Med . 2020 Oct;61(10):1428-1434. doi: 10.2967/jnumed.120.241984. Epub 2020 Aug 28 Comparison of patient stratification by computed tomography radiomics and hypoxia positron emission tomography in head-and-neck cancer radiotherapy Socarrás Fernández JA, Mönnich D, Leibfarth S, Welz S, Zwanenburg A, Leger S, Löck S, Pfannenberg C, La Fougère C, Reischl G, Baumann M, Zips D, Thorwarth D Phys Imaging Radiat Oncol. 2020 Jul;15:52-59. Hydrojet-based delivery of footprint-free iPSC-derived cardiomyocytes into porcine myocardium Weber M, Fech A, Jäger L, Steinle H, Bühler L, Perl RM, Martirosian P, Mehling R, Sonanini D, Aicher WK, Nikolaou K, Schlensak C, Enderle MD, Wendel HP, Linzenbold W, Avci-Adali M Sci Rep. 2020 Oct 8;10(1):16787. doi: 10.1038/s41598-020-73693-x Grassystatin-derived peptides selectively inhibit cathepsin E and have low affinity to cathepsin D Stotz S, Bleher D, Kalbacher H, Maurer A Biochem Biophys Res Commun. 2020 Jun 18;527(1):238-241. doi: 10.1016/j.bbrc.2020.04.070. Epub 2020 May 1 Is there a link between very early changes of primary and secondary lymphoid organs in 18 F-FDG-PET/MRI and treatment response to checkpoint inhibitor therapy? Seith F, Forschner A, Weide B, Gückel B, Schwartz M, Schwenck J, Othman AE, Fenchel M, Garbe C, Nikolaou K, Schwenzer N, la Fougère C, Pfannenberg C J Immunother Cancer. 2020 Aug;8(2):e000656. doi: 10.1136/jitc-2020-000656 Co-registration of optoacoustic tomography and magnetic resonance imaging data from murine tumour models Gehrung M, Tomaszewski M, McIntyre D, Disselhorst J, Bohndiek S Photoacoustics. 2020 Jan 16;18:100147. doi: 10.1016/j.pacs.2019.100147 Advances in the In Vivo Molecular Imaging of Invasive Aspergillosis Gunzer M, Thornton CR, Bézière N Fungi (Basel). 2020 Dec 4;6(4):338. doi: 10.3390/jof6040338 Human Dopaminergic Neurons Lacking PINK1 Exhibit Disrupted Dopamine Metabolism Related to Vitamin B6 Co-Factors Bus C, Zizmare L, Feldkaemper M, ... , Rapaport D, Ueffing M, Casadei N, Krüger R, Gasser T, Vogt Weisenhorn DM, Kahle iScience. 2020 Nov 13;23(12):101797. doi: 10.1016/j.isci.2020.101797 Non-Invasive Assessment of Hypoxia and Neovascularization with MRI for Identification of Aggressive Breast Cancer Bennani-Baiti B, Pinker K, Zimmermann M, Helbich TH, Baltzer PA, Clauser P, Kapetas P, Bago-Horvath Z, Stadlbauer A Cancers (Basel). 2020 Jul 24;12(8):2024 Association between tissue hypoxia, perfusion restrictions, and microvascular architecture alterations with lesion-induced impairment of neurovascular coupling Stadlbauer A, Kinfe TM, Zimmermann M, Eyüpoglu I, Brandner N, Buchfelder M, Zaiss M, Dörfler A, Brandner S J Cereb Blood Flow Metab. 2020 Aug 12:271678X20947546 doi: 10.1177/0271678X20947546. Epub ahead of print. Dual layer doI detector modules for a dedicated mouse brain PET/MRI. Parl C, Kolb A, Stricker-Shaver D, Pichler BJ Phys Med Biol. 2019 Feb 20;64(5):055004. In Vivo Molecular Profiling of Human Glioma : Cross-Sectional Observational Study Using Dynamic Susceptibility Contrast Magnetic Resonance Perfusion Imaging. Hempel JM, Schittenhelm J, Klose U, Bender B, Bier G, Skardelly M, Tabatabai G, Castaneda Vega S, Ernemann U, Brendle C Clin Neuroradiol. 2019 Sep;29(3):479-491. Acetuino-A Handy Open-Source Radiochemistry Module for the Preparation of [1-11C]Acetate. Maurer A, Bowden G, Cotton J, Parl C, Krueger MA, Pichler BJ SLAS Technol. 2019 Jun;24(3):321-329. Comparative immuno-Cerenkov luminescence and -PET imaging enables detection of PSMA+ tumors in mice using 64Cu-radiolabeled monoclonal antibodies. Maier FC, Wild AM, Kirchen N, Holm F, Fuchs K, Schwenck J, Maurer A, Wiehr S Appl Radiat Isot. 2019 Jan;143:149-155. Intention to treat analysis of 68Ga-PSMA and 11C-choline PET/CT versus CT for prostate cancer recurrences after surger. Schwenck J, Olthof SC, Pfannenberg C, Reischl G, Wegener D, Marzec J, Bedke J, Atenzl A, la Fougère C, Zips D, Müller AC J Nucl Med. 2019 Oct;60(10):1359-1365. Prospective evaluation of a tumor control probability model based on dynamic 18F-FMISO PET for head-and-neck cancer radiotherapy. Thorwarth D, Welz S, Mönnich D, Pfannenberg C, Nikolaou K, Reimold M, la Fougère C, Reischl G, Mauz PS, Paulsen F, Alber ML, Belka C, Zips D J Nucl Med. 2019 Dec;60(12):1698-1704. Targeting of the Cholecystokinin-2 Receptor with the Minigastrin Analog 177Lu-DOTA-PP-F11N: Does the Use of Protease Inhibitors Further Improve In Vivo Distribution? Sauter AW, Mansi R, Hassiepen U, Muller L, Panigada T, Wiehr S, Wild AM, Geistlich S, Béhé M, Rottenburger C, Wild D, Fani M J Nucl Med. 2019 Mar;60(3):393-399. Smoking moderates association of 5-HTTLPR and in vivo availability of serotonin transporters. Smolka MN, Reimold M, Kobiella A, Reischl G, Rietschel M, Heinz A Eur Neuropsychopharmacol. 2019 Dec;29(2):171-178. Retrobulbar Sinus Injection of Doxorubicin is More Efficient Than Lateral Tail Vein Injection at Inducing Experimental Nephrotic Syndrome in Mice: A Pilot Study. Bohnert BN, Dörffel T, Daiminger S, Calaminus C, Aidone S, Falkenau A, Semrau A, Le MJ, Iglauer F, Artunc F Lab Anim. 2019 Dec;53(6):564-576. 2-Nitroimidazole-Furanoside Derivatives for Hypoxia Imaging-Investigation of Nucleoside Transporter Interaction, F-Labeling and Preclinical PET Imaging. Maier FC, Schweifer A, Damaraju VL, Cass CE, Bowden GD, Ehrlichmann W, Kneilling M, Pichler BJ, Hammerschmidt F, Reischl G Pharmaceuticals (Basel). 2019 Feb 15;12(1). Reproducibility and comparability of preclinical PET imaging data: A multi-center small animal PET study. Mannheim JG, Mamach M, Reder S, Traxl A, Mucha N, Disselhorst JA, Mittelhäuser M, Kuntner C, Thackeray JT, Ziegler S, Wanek T, Bankstahl JP, Pichler BJ J Nucl Med. 2019 Oct;60(10):1483-1491. Evaluation of the therapeutic potential of the selective p38 MAPK inhibitor Skepinone-L and the dual p38/JNK 3 inhibitor LN 950 in experimental K/BxN serum transfer arthritis. Guenthoer P, Fuchs K, Reischl G, Quintanilla-Martinez L, González-Menéndez I, Laufer S, Pichler BJ, Kneilling M Inflammopharmacology. 2019 Dec;27(6):1217-1227. Functional resting-state brain connectivity is accompanied by dynamic correlations of application-dependent [18F]FDG PET-tracer fluctuations. Amend M, Ionescu TM, Di X, Pichler BJ, Biswal BB, Wehrl HF Neuroimage. 2019 Aug 1;196:161-172. The administration route of tumor-antigen-specific T-helper cells differentially modulates the tumor microenvironment and senescence. Griessinger CM, Schmid AM, Sonanini D, Schörg BF, Jarboui MA, Bukala D, Mucha N, Fehrenbacher B, Steinhilber J, Martella M, Kohlhofer U, Schaller M, Zender L, Rammensee HG, Quintanilla-Martinez L, Röcken M, Kneilling M, Pichler BJ Carcinogenesis. 2019 Apr 29;40(2):289-302. Data Curation for Preclinical and Clinical Multimodal Imaging Studies. Yamoah GG, Cao L, Wu CW, Beekman FJ, Vandeghinste B, Mannheim JG, Rosenhain S, Leonardic K, Kiessling F, Gremse F Mol Imaging Biol. 2019 Dec;21(6):1034-1043. Imaging fibrosis in inflammatory diseases: targeting the exposed extracellular matrix. Beziere N, Fuchs K, Maurer M, Reischl G, Brück J, Ghoreschi K, Fehrenbacher B, Carvajal Berrio D, Schenke-Leyland K, Kohlhofer U, Quintanilla-Martinez L, Gawaz M, Kneilling M, Pichler BJ Theranostics. 2019 Apr 13;9(10):2868-2881. Enhanced Central Neural Gain Compensates Acoustic Trauma-induced Cochlear Impairment, but Unlikely Correlates with Tinnitus and Hyperacusis. Möhrle D, Hofmeier B, Amend M, Wolpert S, Ni K, Bing D, Klose U, Pichler BJ, Knipper M, Rüttiger L Neuroscience. 2019 May 21;407:146-169. Fast enzymatic synthesis of n.c.a. 6-[18 F]fluorodopamine (FDA) from n.c.a. 6-[18 F]FDOPA and the fate of 6-FDOPA and 6-FDA in neuroblastoma and Caki-1 cells after their uptake. Kuçi Z, Ehrlichmann W, Sauer J, Handgretinger R, Bruchelt G, Reischl G J Labelled Comp Radiopharm. 2019 Jun 30;62(8):438-447. Smart MRI Agents for Detecting Extracellular Events In Vivo: Progress and Challenges. Parrott D, Shirangi Fernando W, Martins A Inorganics 2019; 7(2), 18. Quantitative Rodent Brain Receptor Imaging. Herfert K, Mannheim JG, Kuebler L, Marciano S, Amend M, Parl C, Napieczynska H, Maier FM, Vega SC, Pichler BJ Mol. Imaging Biol. 2019 Apr; 22(2):223-244. A Responsive Magnetic Resonance Imaging Contrast Agent for Detection of Excess Copper(II) in the Liver In Vivo. Paranawithana NN, Martins AF, Clavijo Jordan V, Zhao P, Chirayil S, Meloni G, Sherry AD J Am Chem Soc. 2019 Jul 17;141(28):11009-11018. Synchrotron Radiation X-ray Fluorescence Elemental Mapping in Healthy versus Malignant Prostate Tissues Provides New Insights into the Glucose-Stimulated Zinc Trafficking in the Prostate As Discovered by MRI. Clavijo Jordan V, Al-Ebraheem A, Geraki K, Dao E, Martins AF, Chirayil S, Farquharson M, Sherry AD Inorg Chem. 2019 Oct 21;58(20):13654-13660. A Design of Experiments (DoE) Approach Accelerates the Optimization of Copper-Mediated 18F-Fluorination Reactions of Arylstannanes. Bowden GD, Pichler BJ, Maurer A Sci Rep. 2019 Aug 6;9(1):11370. Interregional causal influences of brain metabolic activity reveal the spread of aging effects during normal aging. Di X, Wölfer M, Amend M, Wehrl H, Ionescu TM, Pichler BJ, Biswal BB Hum Brain Mapp. 2019 Nov 1;40(16):4657-4668. Cysteine-type cathepsins promote the effector phase of acute cutaneous delayed-type hypersensitivity reactions. Schwenck J, Maurer A, Fehrenbacher B, Mehling R, Knopf P, Mucha N, Haupt D, Fuchs K, Griessinger CM, ..., Röcken M, Kalbacher H, Pichler BJ, Kneilling M Theranostics. 2019 May 31;9(13):3903-3917. Weak Agonistic LPS Restores Intestinal Immune Homeostasis. Steimle A, Michaelis L, Di Lorenzo F, Kliem T, Münzner T, Maerz JK, Schäfer A, Lange A, Parusel R, Gronbach K, Fuchs K, Silipo A, Öz HH, Pichler BJ, Autenrieth IB, Molinaro A, Frick JS Mol Ther. 2019 Nov 6;27(11):1974-1991. Visualization and quantification of in vivo homing kinetics of myeloid-derived suppressor cells in primary and metastatic cancer. Hoffmann SHL, Reck D, Maurer A, Fehrenbacher B, Sceneay JE, Poxleitner M, Öz HH, Ehrlichmann W, Reischl G, Fuchs K, Schaller M, Hartl D, Kneilling M, Möller A, Pichler BJ, Griessinger CM Theranostics. 2019 Aug 12;9(20):5869-5885. Special Issue "Targets, Tracers and Translation Novel Radiopharmaceuticals Boost Nuclear Medicine" Reischl G Pharmaceuticals (Basel). 2019 Jul 18;12(3). pii: E111. Transcriptional and metabolic rewiring of colorectal cancer cells expressing the oncogenic KRASG13D mutation. Charitou T, Srihari S, Lynn MA, Jarboui MA, Fasterius E, Moldovan M, Shirasawa S, Tsunoda T, Ueffing M, Xie J, Xin J, Wang X, Proud CG, Boldt K, Al-Khalili Szigyarto C, Kolch W, Lynn DJ Br J Cancer. 2019 Jul;121(1):37-50. GD2-targeted chimeric antigen receptor T cells prevent metastasis formation by elimination of breast cancer stem-like cells. Seitz CM, Schroeder S, Knopf P, Krahl AC, Hau J, Schleicher S, Martella M, Quintanilla-Martinez L, Kneilling M, Pichler BJ, Lang P, Atar D, Schilbach K, Handgretinger R, Schlegel P Oncoimmunology 2019 Nov; 9(1): 1683345 Assessment of Proteolytic Activities in the Bone Marrow Microenvironment. Maurer A, Klein G, Staudt ND Methods Mol Biol. 2019;2017:149-163. The yin and yang of imaging tumor associated macrophages with PET and MRI. Mukherjee S, Sonanini D, Maurer A, Daldrup-Link HE Theranostics. 2019 Oct 15;9(25):7730-7748. 3D-printed standardized phantoms for small animal PET and MRI: a comparison study. Zell F, Mannheim J, Grehn M, Rafecas M Trans. AMMM 2019; 1(1) A new synthetic toll-like receptor 1/2 ligand is an efficient adjuvant for peptide vaccination in a human volunteer. Rammensee HG, Wiesmüller KH, Chandran PA, Zelba H, Rusch E, Gouttefangeas C, Kowalewski DJ, ...,Schwenck J, Weber ANR, Pichler BJ, Kneilling M, la Fougère C, Forchhammer S, Metzler G, Bauer J, Weide B, Schippert W, Stevanović S, Löffler MW. J Immunother Cancer. 2019 Nov; 7(1):307. Standardization of Small Animal Imaging-Current Status and Future Prospects. Mannheim JG, Kara F, Doorduin J, Fuchs K, Reischl G, Liang S, Verhoye M, Gremse F, Mezzanotte L, Huisman MC Mol Imaging Biol. 2018 Oct;20(5):716-731 In vivo imaging of tumor-infiltrating immune cells: implications for cancer immunotherapy. Zeelen C, Paus C, Draper D, Heskamp S, Signore A, Galli F, Griessinger CM, Aarntzen EH Q J Nucl Med Mol Imaging. 2018 Mar;62(1):56-77. CCR2-dependent Gr1high monocytes promote kidney injury in shiga toxin-induced hemolytic uremic syndrome in mice. Pohl JM, Volke JK, Thiebes S, Brenzel A, Fuchs K, Beziere N, Ehrlichmann W, Pichler BJ, Squire A, Gueler F, Engel DR Eur J Immunol. 2018 Jun;48(6):990-1000. Evaluation of the accuracy of nine electronic apex locators by using Micro-CT. Connert T, Judenhofer MS, Hülber-J M, Schell S, Mannheim JG, Pichler BJ, Löst C, ElAyouti A Int Endod J. 2018 Feb;51(2):223-232. Comparison of the Accuracy of FMT/CT and PET/MRI for the Assessment of Antibody Biodistribution in Squamous Cell Carcinoma Xenografts. Hage C, Gremse F, Griessinger CM, Maurer A, Hoffmann SHL, Osl F, Pichler BJ, Kiessling F, Scheuer W, Pöschinger T J Nucl Med. 2018 Jan;59(1):44-50. Combined PET/MRI: Global Warming-Summary Report of the 6th International Workshop on PET/MRI, March 27-29, 2017, Tübingen, Germany. Bailey DL, Pichler BJ, Gueckel B, Antoch G, Barthel H, Bhujwalla ZM, Biskup S, Biswal S, Bitzer M, Boellaard R, Braren RF, Brendle C, Brindle K, Chiti A, la Fougère C, Gillies R, Goh V, Goyen M, Hacker M, Heukamp L, Knudsen GM, Krackhardt AM, Law I et al. Mol Imaging Biol. 2018 Feb;20(1):4-20. Optimization, evaluation and calibration of a cross-strip DOI detector. Schmidt FP, Kolb A, Pichler BJ Phys Med Biol. 2018 Feb 20;63(4):045022. Impact of the AIF Recording Method on Kinetic Parameters in Small Animal PET. Napieczynska H, Kolb A, Katiyar P, Tonietto M, Ud-Dean M, Stumm R, Herfert K, Calaminus C, Pichler B J Nucl Med. 2018 Jul;59(7):1159-1164. The effects of taxanes, vorinostat and doxorubicin on growth and proliferation of Echinococcus multilocularis metacestodes assessed with magnetic resonance imaging and simultaneous positron emission tomography. Huang X, Wiehr S, Wild AM, Voßberg P, Hoffmann W, Grüner B, Köhler C, Soboslay PT Oncotarget. 2018 Jan 10;9(10):9073-9087. Tracking the fate of adoptively transferred myeloid-derived suppressor cells in the primary breast tumor microenvironment. Sceneay J, Griessinger CM, Hoffmann SHL, Wen SW, Wong CSF, Krumeich S, Kneilling M, Pichler BJ, Möller A PLoS One. 2018 Apr 20;13(4):e0196040. Linking imaging to omics utilizing image-guided tissue extraction. Disselhorst JA, Krueger MA, Ud-Dean SMM, Bezrukov I, Jarboui MA, Trautwein C, Traube A, Spindler C, Cotton JM, Leibfritz D, Pichler BJ Proc Natl Acad Sci U S A. 2018 Mar 27;115(13):E2980-E2987. Hybrid cardiac imaging using PET/MRI: a joint position statement by the European Society of Cardiovascular Radiology (ESCR) and the European Association of Nuclear Medicine (EANM). Nensa F, Bamberg F, Rischpler C, Menezes L, Poeppel TD, la Fougere C, Beitzke D, Rasul S, Loewe C, Nikolaou K, Bucerius J, Kjaer A, Gutberlet M, Prakken NH, Vliegenthart R, Slart RHJA, Nekolla SG, Lassen ML, Pichler BJ, Schlosser T, Jacquier A, et al. Eur Radiol. 2018 Oct;28(10):4086-4101. Glioma grading by dynamic susceptibility contrast perfusion and 11C-methionine positron emission tomography using different regions of interest. Brendle C, Hempel JM, Schittenhelm J, Skardelly M, Reischl G, Bender B, Ernemann U, la Fougère C, Klose U Neuroradiology. 2018 Apr;60(4):381-389. PET/MRI Hybrid Systems. Mannheim JG, Schmid AM, Schwenck J, Katiyar P, Herfert K, Pichler BJ, Disselhorst JA Semin Nucl Med. 2018 Jul;48(4):332-347. Oxygen-enhanced and dynamic contrast-enhanced optoacoustic tomography provide surrogate biomarkers of tumour vascular function, hypoxia and necrosis. Tomaszewski MR, Gehrung M, Joseph J, Quiros Gonzalez I, Disselhorst JA, Bohndiek SE Cancer Res. 2018 Oct 15;78(20):5980-5991. Pre-clinical Imaging of Invasive Candidiasis Using ImmunoPET/MR. Morad HOJ, Wild AM, Wiehr S, Davies G, Maurer A, Pichler BJ, Thornton CR Front Microbiol. 2018 Aug 23;9:1996. The Potential of In Vivo Imaging for Optimization of Molecular and Cellular Anti-cancer Immunotherapies. Fruhwirth GO, Kneilling M, de Vries IJM, Weigelin B, Srinivas M, Aarntzen EHJG Mol Imaging Biol. 2018 Oct;20(5):696-704. Fast non-enhanced abdominal examination protocols in PET/MRI for patients with neuroendocrine tumors (NET): comparison to multiphase contrast-enhanced PET/CT. Seith F, Schraml C, Reischl G, Nikolaou K, Pfannenberg C, la Fougère C, Schwenzer N Radiol Med. 2018 Nov;123(11):860-870. In vivo assessment of tumor heterogeneity in WHO 2016 glioma grades using diffusion kurtosis imaging: Diagnostic performance and improvement of feasibility in routine clinical practice. Hempel JM, Schittenhelm J, Bisdas S, Brendle C, Bender B, Bier G, Skardelly M, Tabatabai G, Castaneda Vega S, Ernemann U, Klose U J Neuroradiol. 2018 Feb;45(1):32-40. Tumor-draining lymph nodes are pivotal in PD-1/PD-L1 checkpoint therapy. Fransen MF, Schoonderwoerd M, Knopf P, Camps MG, Hawinkels LJ, Kneilling M, van Hall T, Ossendorp F JCI Insight. 2018 Dec 6;3(23). Effect of Perfusion on Diffusion Kurtosis Imaging Estimates for In Vivo Assessment of Integrated 2016 WHO Glioma Grades : A Cross-Sectional Observational Study. Hempel JM, Schittenhelm J, Brendle C, Bender B, Bier G, Skardelly M, Tabatabai G, Castaneda Vega S, Ernemann U, Klose U Clin Neuroradiol. 2018 Dec;28(4):481-491. Comparison of 68Ga-labelled PSMA-11 and 11C-choline in the detection of prostate cancer metastases by PET/CT. Schwenck J, Rempp H, Reischl G, Kruck S, Stenzl A, Nikolaou K, Pfannenberg C, la Fougère C Eur J Nucl Med Mol Imaging. 2017 Jan;44(1):92-101 Low μ-Opioid Receptor Status in Alcohol Dependence Identified by Combined Positron Emission Tomography and Post-Mortem Brain Analysis. Hermann D, Hirth N, Reimold M, Batra A, Smolka MN, Hoffmann S, Kiefer F, Noori HR, Sommer WH, Reischl G, la Fougère C, Mann K, Spanagel R, Hansson AC Neuropsychopharmacology. 2017 Feb;42(3):606-614 [68Ga]NOTA-Galactosyl Human Serum Albumin: a Tracer for Liver Function Imaging with Improved Stability Haubner R, Schmid AM, Maurer A, Rangger C, Roig LG, Pichler BJ, Virgolini IJ Mol Imaging Biol. 2017 Oct;19(5):723-730. In vivo hypoxia PET imaging quantifies the severity of arthritic joint inflammation in line with overexpression of HIF and enhanced ROS generation Fuchs K, Kuehn A, Mahling M, Guenthoer P, Hector A, Hartl D, Laufer S, Kohlhofer U, Quintanilla-Martinez L, Reischl G, Röcken M, Pichler BJ, Kneilling M. J Nucl Med. 2017 May;58(5):853-860. β-[18F]Fluoro Azomycin Arabinoside (β-[18F]FAZA): Synthesis, radiofluorination and preliminary PET imaging of murine A431 tumors. Kumar P, Roselt P, Reischl G, Cullinane C, Beiki D, Ehrlichmann W, Binns D, Naimi E, Yang J, Hicks R, Machulla HJ, Wiebe LI. Curr Radiopharm. 2017;10(2):93-101. In vivo molecular profiling of human glioma using diffusion kurtosis imaging. Hempel JM, Bsidas S, Schlittenhelm J, Brendle C, Bender B, Wassmann H, Skardelly M, Tabatabai G, Vega SC, Ernemann U, Klose U. J Neurooncol. Jan;131(1):93-101. Spectral Clustering Predicts Tumor Tissue Heterogeneity Using Dynamic 18F-FDG PET: A Complement to the Standard Compartmental Modeling Approach Katiyar P, Divine MR, Kohlhofer U, Quintanilla-Martinez L, Schölkopf B, Pichler BJ, Disselhorst JA. J Nucl Med. Apr; 58(4):651-657. Comparison of DCE-MRI kinetic parameters and FMISO-PET uptake parameters in head and neck cancer patients. Simoncic U, Leibfarth S, Welz S, Schwenzer N, Schmidt H, Reischl G, Pfannenberg C, Fougère C, Nikolaou K, Zips D, Thorwarth D Med Phys. 2017 Jun;44(6):2358-2368. Influence of Co-57 and CT Transmission Measurements on the Quantification Accuracy and Partial Volume Effect of a Small Animal PET Scanner Mannheim JG, Schmid AM, Pichler BJ. Mol Imaging Biol. 2017 Dec;19(6):825-836. Marginal zone B cells control the response of follicular helper T cells to a high-cholesterol diet. Nus M, Sage AP, Lu Y, Masters L, Lam BYH, Newland S, Weller S, Tsiantoulas D, Raffort J, Marcus D, Finigan A, Kitt L, Figg N, Schirmbeck R, Kneilling M, Yeo GSH, Binder CJ, de la Pompa JL, Mallat Z. Nat Med. May;23(5):601-610 A Novel Unsupervised Segmentation Approach Quantifies Tumor Tissue Populations Using Multiparametric MRI: First Results with Histological Validation. Katiyar P, Divine MR, Kohlhofer U, Quintanilla-Martinez L, Schölkopf B, Pichler BJ, Disselhorst JA Mol Imaging Biol. Jun;19(3):391-397 Characterization of a Novel Murine Model for Spontaneous Hemorrhagic Stroke using in vivo PET and MR multiparametric imaging. Vega SC, Weinl C, Calaminus C, Wang L, Harant M, Ehrlichmann W, Thiele D, Kohlhofer U, Reischl G, Hempel JM, Ernemann U, Quintanilla Martinez L, Nordheim A, Pichler BJ Neuroimage. 2017 Jul 15;155:245-256. Prognostic value of dynamic hypoxia PET in head and neck cancer: Results from a planned interim analysis of a randomized phase II hypoxia-image guided dose escalation trial. Welz S, Mönnich D, Pfannenberg C, Nikolaou K, Reimold M, La Fougère C, Reischl G, Mauz PS, Paulsen F, Alber M, Belka C, Zips D, Thorwarth D Radiother Oncol. 2017 Sep;124(3):526-532. Do all roads lead to Rome? A comparison of brain networks derived from inter-subject volumetric and metabolic covariance and moment-to-moment hemodynamic correlations in old individuals. Di X, Gohel S, Thielcke A, Wehrl HF, Biswal BB Brain Struct Funct. 2017 Nov;222(8):3833-3845. Murine Lymphocyte Labeling by 64Cu-Antibody Receptor Targeting for In Vivo Cell Trafficking by PET/CT. Hoffmann SHL, Maurer A, Reck DI, Reischl G, Pichler BJ, Kneilling M, Griessinger CM J Vis Exp. Apr 29;(122) Non-invasive In Vivo Fluorescence Optical Imaging of Inflammatory MMP Activity Using an Activatable Fluorescent Imaging Agent. Schwenck J, Maier FC, Kneilling M, Wiehr S, Fuchs K J Vis Exp. May 8;(123) Overlap of highly FDG-avid and FMISO hypoxic tumor subvolumes in patients with head and neck cancer. Mönnich D, Thorwarth D, Leibfarth S, Pfannenberg C, Reischl G, Mauz PS, Nikolaou K, la Fougère C, Zips D, Welz S Acta Oncol. 2017 Nov;56(11):1577-1582. Validity of longitudinal sections for determining the apical constriction. Schell S, Judenhofer MS, Mannheim JG, Hülber-J M, Löst C, Pichler BJ, ElAyouti A Int Endod J. Jul;50(7):706-712 Imaging neuronal pathways with 52Mn PET: Toxicity evaluation in rats. Napieczynska H, Severin GW, Fonslet J, Wiehr S, Menegakis A, Pichler BJ, Calaminus C Neuroimage. Jun 30;158:112-125 Gender differences in cerebral metabolism for color processing in mice: A PET/MRI Study. Njemanze PC, Kranz M, Amend M, Hauser J, Wehrl H, Brust P PLoS One. 2017 Jul 19;12(7):e0179919. A novel optically transparent RF shielding for fully integrated PET/MRI systems. Parl C, Kolb A, Schmid AM, Wehrl HF, Disselhorst JA, Soubiran PD, Stricker-Shaver D, Pichler BJ. Phys Med Biol. Sep 1;62(18):7357-7378. Cre/lox-assisted non-invasive in vivo tracking of specific cell populations by positron emission tomography. Thunemann M, Schörg BF, Feil S, Lin Y, Voelkl J, Golla M, Vachaviolos A, Kohlhofer U, Quintanilla-Martinez L, Olbrich M, Ehrlichmann W, Reischl G, Griessinger CM, Langer HF, Gawaz M, Lang F, Schäfers M, Kneilling M, Pichler BJ, Feil R Nat Commun. Sep 5;8(1):444 Geometric analysis of loco-regional recurrences in relation to pre-treatment hypoxia in patients with head and neck cancer Boeke S, Thorwarth D, Mönnich D, Pfannenberg C, Reischl G, La Fougère C, Nikolaou K, Mauz PS, Paulsen F, Zips D, Welz S Acta Oncol. 2017 Nov;56(11):1571-1576. SUV-quantification of physiological lung tissue in an integrated PET/MR-system: Impact of lung density and bone tissue. Seith F, Schmidt H, Gatidis S, Bezrukov I, Schraml C, Pfannenberg C, la Fougère C, Nikolaou K, Schwenzer N PLoS One. 2017 May 31;12(5):e0177856. Towards Translational ImmunoPET/MR Imaging of Invasive Pulmonary Aspergillosis: The Humanised Monoclonal Antibody JF5 Detects Aspergillus Lung Infections In Vivo. Davies G, Rolle AM, Maurer A, Spycher PR, Schillinger C, Solouk-Saran D, Hasenberg M, Weski J, Fonslet J, Dubois A, Boschetti F, Denat F, Gunzer M, Eichner M, Ryder LS, Jensen M, Schibli R, Pichler BJ, Wiehr S, Thornton CR Theranostics. Aug 11;7(14):3398-3414 Extracellular Cyclophilin A Augments Platelet-Dependent Thrombosis and Thromboinflammation. V Ungern-Sternberg SNI, Vogel S, Walker-Allgaier B, Geue S, Maurer A, Wild AM, Münzer P, Chatterjee M, Heinzmann D, Kremmer E, Borst O, Loughran P, Zernecke A, Neal MD, Billiar TR, Gawaz M, Seizer P Thromb Haemost. 2017 Nov;117(11):2063-2078. Histogram analysis of diffusion kurtosis imaging estimates for in vivo assessment of 2016 WHO glioma grades: A cross-sectional observational study. Hempel JM, Schittenhelm J, Brendle C, Bender B, Bier G, Skardelly M, Tabatabai G, Castaneda Vega S, Ernemann U, Klose U Eur J Radiol. 2017 Oct;95:202-211. Carboxypeptidase E transmits its anti-migratory function in glioma cells via transcriptional regulation of cell architecture and motility regulating factors. Armento A, Ilina EI, Kaoma T, Muller A, Vallar L, Niclou SP, Krüger MA, Mittelbronn M, Naumann U Int J Oncol. 2017 Aug;51(2):702-714. Acetazolamide sensitive tissue calcification and aging of klotho-hypomorphic mice Leibrock CB, Alesutan I, Voelkl J, Michael D, Castor T, Kohlhofer U, Quintanilla-Martinez L, Kübler L, Mannheim JG, Pichler BJ, Rosenblatt KP, Kuro-O M, Lang F. J Mol Med (Berl). 2016 Jan;94(1):95-106. Comprehensive Oncologic Imaging in Infants and Preschool Children With Substantially Reduced Radiation Exposure Using Combined Simultaneous 18F-Fluorodeoxyglucose Positron Emission Tomography/Magnetic Resonance Imaging: A Direct Comparison to 18F-Fluor Gatidis S, Schmidt H, Gücke B, Bezrukov I, Seitz G, Ebinger M, Reimold M, Pfannenberg CA, Nikolaou K, Schwenzer NF, Schäfer JF. Invest Radiol. 2016 Jan;51(1):7-14. [Simultaneous whole-body PET-MRI in pediatric oncology : More than just reducing radiation?]. Gatidis S, Gückel B, la Fougère C, Schmitt J, Schäfer JF. Radiologe. 2016 Jul;56(7):622-30. A Nexus Consisting of Beta-Catenin and Stat3 Attenuates BRAF Inhibitor Efficacy and Mediates Acquired Resistance to Vemurafenib. Sinnberg T, Makino E, Krueger MA, Velic A, Macek B, Rothbauer U, Groll N6, Pötz O, Czemmel S, Niessner H, Meier F, Ikenberg K, Garbe C, Schittek B. EBioMedicine. 2016 Jun;8:132-49. A Population-Based Gaussian Mixture Model Incorporating 18F-FDG PET and Diffusion-Weighted MRI Quantifies Tumor Tissue Classes. Divine MR, Katiyar P, Kohlhofer U, Quintanilla-Martinez L, Pichler BJ, Disselhorst JA J Nucl Med. 2016 Mar;57(3):473-9. Combined PET/MRI: from Status Quo to Status Go. Summary Report of the Fifth International Workshop on PET/MR Imaging; February 15-19, 2016; Tübingen, Germany. Bailey DL, Pichler BJ, Gückel B, Barthel H, Beer AJ, Botnar R, Gillies R, Goh V, Gotthardt M, Hicks RJ, Lanzenberger R, la Fougere C, Lentschig M, Nekolla SG, Niederdraenk T, Nikolaou K, Nuyts J, Olego D, Riklund KÅ, Signore A, Schäfers M, Sossi V, et al. Mol Imaging Biol. 2016 Oct;18(5):637-50. Comparison of Positron Emission Tomography Quantification Using Magnetic Resonance- and Computed Tomography-Based Attenuation Correction in Physiological Tissues and Lesions: A Whole-Body Positron Emission Tomography/Magnetic Resonance Study in 66 Patient Seith F, Gatidis S, Schmidt H, Bezrukov I, la Fougère C, Nikolaou K, Pfannenberg C, Schwenzer N. Invest Radiol. 2016 Jan;51(1):66-71. Comparison of small animal CT contrast agents Mannheim JG, Schlichthaerle T, Kuebler L, Quintanilla-Martinez L, Kohlhofer U, Kneilling M, Pichler BJ Contrast Media Mol Imaging. 2016 Jul;11(4):272-84. Comparison of Tumor Uptake Heterogeneity Characterization Between Static and Parametric 18F-FDG PET Images in Non-Small Cell Lung Cancer Tixier F, Vriens D, Cheze-Le Rest C, Hatt M, Disselhorst JA, Oyen WJ, de Geus-Oei LF, Visser EP, Visvikis D. J Nucl Med. 2016 Jul;57(7):1033-9. Correlation between positron emission tomography and Cerenkov luminescence imaging in vivo and ex vivo using 64Cu-labeled antibodies in a neuroblastoma mouse model. Maier FC, Schmitt J, Maurer A, Ehrlichmann W, Reischl G, Nikolaou K, Handgretinger R, Pichler BJ, Thaiss WM. Oncotarget. 2016 Oct 11;7(41):67403-67411 CXCR1 Regulates Pulmonary Anti-Pseudomonas Host Defense. Carevic M, Öz H, Fuchs K, Laval J, Schroth C, Frey N, Hector A, Bilich T, Haug M, Schmidt A, Autenrieth SE, Bucher K, Beer-Hammer S, Gaggar A, Kneilling M, Benarafa C, Gao JL, Murphy PM, Schwarz S, Moepps B, Hartl D. J Innate Immun. 2016;8(4):362-73 Decoding intratumoral heterogeneity of breast cancer by multiparametric in vivo imaging: A translational study. Schmitz J, Schwab J, Schwenck J, Chen Q, Quintanilla-Martinez L, Hahn M, Wietek B, Schwenzer N, Staebler A, Kohlhofer U, Aina OH, Hubbard NE, Reischl G, Borowsky AD, Brucker S, Nikolaou K, La Fougère C, Cardiff RD, Pichler BJ, Schmid AM Cancer Res. 2016 Sep 15;76(18):5512-22. Enhanced binding of necrosis-targeting immunocytokine NHS-IL12 after local tumor irradiationin murine xenograft models. Eckert F, Schmitt J, Zips D, Krueger MA, Pichler BJ, Gillies SD, Strittmatter W, Handgretinger R, Schilbach K Cancer Immunol Immunother. 2016 Aug;65(8):1003-13. Fluorescence and Cerenkov luminescence imaging. Applications in small animal research. Schwenck J, Fuchs K, Eilenberger SH, Rolle AM, Castaneda Vega S, Thaiss WM, Maier FC. Nuklearmedizin. 2016;55(2):63-70. ImmunoPET/MR imaging allows specific detection of Aspergillus fumigatus lung infection in vivo Rolle AM, Hasenberg M, Thornton CR, Solouk-Saran D, Männ L, Weski J, Maurer A, Fischer E, Spycher PR, Schibli R, Boschetti F, Stegemann-Koniszewski S, Bruder D, Severin GW, Autenrieth SE, Krappmann S, Davies G, Pichler BJ, Gunzer M, Wiehr S. Proc Natl Acad Sci U S A. 2016 Feb 23;113(8):E1026-33 In Vivo Evaluation of [11C]DASB for Quantitative SERT Imaging in Rats and Mice Walker M, Ehrlichmann W, Stahlschmidt A, Pichler B, Fischer K. J Nucl Med. 2016 Jan;57(1):115-21. Necrotic Cell Sensor Clec4e Promotes a Pro-Atherogenic Macrophage Phenotype Through Activation of the Unfolded Protein Response Clément M, Basatemur G, Masters L, Baker L, Bruneval P, Iwawaki T, Kneilling M, Yamasaki S, Goodall J, Mallat Z Circulation. 2016 Oct 4;134(14):1039-1051 New pathogen-specific immunoPET/MR tracer for molecular imaging of a systemic bacterial infection Wiehr S, Warnke P, Rolle AM, Schütz M, Oberhettinger P, Kohlhofer U, Quintanilla-Martinez L, Maurer A, Thornton C, Boschetti F, Reischl G, Autenrieth IB, Pichler BJ, Autenrieth SE Oncotarget. 2016 Mar 8;7(10):10990-1001. PI3K pathway inhibition achieves potent antitumor activity in melanoma brain metastases in vitro and in vivo. Niessner H, Schmitz J, Tabatabai G, Schmid A, Calaminus C, Sinnberg T, Weide B, Eigentler TK, Garbe C, Schittek B, Quintanilla-Fend L, Bender B, Mai M, Praetorius C, Beissert S, Schackert G,..., Pichler BJ,...,Meier F Clin Cancer Res. 2016 Dec 1;22(23):5818-5828 PI3K-resistant GSK3 controls adiponectin formation and protects from metabolic syndrome. Chen H; Fajol A; Hoene M; Zhang B; Schleicher ED; Lin Y; Calaminus C; Pichler BJ; Weigert C; Haring HU; Lang F; Foller, M Proc Natl Acad Sci U S A. 2016 May 17;113(20):5754-9. Preclinical evaluation of the anti-tumor effects of the natural isoflavone genistein in two xenograft mouse models monitored by [18F]FDG, [18F]FLT, and [64Cu]NODAGA-cetuximab small animal PET. Honndorf VS, Wiehr S, Rolle AM, Schmitt J, Kreft L, Quintanilla-Martinez L, Kohlhofer U, Reischl G, Maurer A, Boldt K, Schwarz M, Schmidt H, Pichler BJ Oncotarget. 2016 May 10;7(19):28247-61. The emerging role of myeloid-derived suppressor cells in lung diseases. Kolahian S, Öz HH, Zhou B, Griessinger CM, Rieber N, Hartl D. Eur Respir J. 2016 Mar;47(3):967-77. The Synergistic Effect of Selumetinib/Docetaxel Combination Therapy Monitored by [(18)F]FDG/[(18)F]FLT PET and Diffusion-Weighted Magnetic Resonance Imaging in a Colorectal Tumor Xenograft Model. Honndorf VS, Schmidt H, Wiehr S, Wehrl HF, Quintanilla-Martinez L, Stahlschmidt A, Barjat H, Emmas SA, Pichler BJ Mol Imaging Biol. 2016 Apr;18(2):249-57. The Positron Emission Tomography Tracer 3'-Deoxy-3'-[18F]Fluorothymidine ([18F]FLT) Is Not Suitable to Detect Tissue Proliferation Induced by Systemic Yersinia enterocolitica Infection in Mice Wiehr S, Rolle AM, Warnke P, Kohlhofer U, Quintanilla-Martinez L, Reischl G, Autenrieth IB, Pichler BJ, Autenrieth SE PLoS One. 2016 Oct 4;11(10):e0164163. [18F]Fluoro-azomycin-2´-deoxy-β-d-ribofuranoside - A new imaging agent for tumor hypoxia in comparison with [18F]FAZA Schweifer A, Maier F, Ehrlichmann W, Lamparter D, Kneilling M, Pichler BJ, Hammerschmidt F, Reischl G Nucl Med Biol. 2016 Dec;43(12):759-769 Structural and molecular myelination deficits occur prior to neuronal loss in the YAC128 and BACHD models of Huntington disease Teo RT, Hong X, Yu-Taeger L, Huang Y, Tan LJ, Xie Y, To XV, Guo L, Rajendran R, Novati A, Calaminus C, Riess O, Hayden MR, Nguyen HP, Chuang KH, Pouladi MA Hum Mol Genet. 2016 Jul 1;25(13):2621-2632 First protein and peptide characterization of the tarsal adhesive secretions in the desert locust, Schistocerca gregaria, and the Madagascar hissing cockroach, Gromphadorhina portentosa Betz O, Maurer A, Verheyden AN, Schmitt C, Kowalik T, Braun J, Grunwald I, Hartwig A, Neuenfeldt M 2016 Oct;25(5):541-9 Symbiotic gut commensal bacteria act as host cathepsin S activity regulators Steimle A, Gronbach K, Beifuss B, Schäfer A, Harmening R, Bender A, Maerz JK, Lange A, Michaelis L, Maurer A, Menz S, McCoy K, Autenrieth IB, Kalbacher H, Frick JS J Autoimmun. 2016 Dec;75:82-95 Improved selectivity of mIBG uptake into neuroblastoma cells in vitro and in vivo by inhibition of organic cation transporter 3 uptake using clinically approved corticosteroids Bayer M, Schmitt J, Dittmann H, Handgretinger R, Bruchelt G, Sauter AW Nucl Med Biol. 2016 Sep;43(9):543-51 Combined PET/MR: A Technology Becomes Mature Wehrl HF, Sauter AW, Divine MR, Pichler BJ. J Nucl Med. 2015 Feb. 56(2):165-8. The impact of weakly bound 89Zr on preclinical studies: Non-specific accumulation in solid tumors and aspergillus infection Severin GW, Jørgensen JT, Wiehr S, Rolle AM, Hansen AE, Maurer A, Hasenberg M, Pichler B, Kjaer A, Jensen AI. Nucl Med Biol. 2015 Apr;42(4):360-8. Image-derived biomarkers and multimodal imaging strategies for lung cancer management Sauter AW, Schwenzer N, Divine MR, Pichler BJ, Pfannenberg C. Eur J Nucl Med Mol Imaging. 2015 Apr;42(4):634-43. Evaluation of the Metabolic Activity of Echinococcus multilocularis in Rodents Using Positron Emission Tomography Tracers Rolle AM, Soboslay PT, Reischl G, Hoffmann WH, Pichler BJ, Wiehr S. Mol Imaging Biol. 2015 Aug;17(4):512-20. 64Cu antibody-targeting of the T-cell receptor and subsequent internalization enables in vivo tracking of lymphocytes by PET Griessinger CM, Maurer A, Kesenheimer C, Kehlbach R, Reischl G, Ehrlichmann W, Bukala D, Harant M, Cay F, Brück J, Nordin R, Kohlhofer U, Rammensee HG, Quintanilla-Martinez L, Schaller M, Röcken M, Pichler BJ, Kneilling M. Proc Natl Acad Sci U S A. 2015 Jan 27. 112(4):1161-6. In vivo visualization of prostate-specific membrane antigen in glioblastoma Schwenck J, Tabatabai G, Skardelly M, Reischl G, Beschorner R, Pichler B, la Fougère C. Eur J Nucl Med Mol Imaging. 2015 Jan. 42(1):170-1. Assessment of murine brain tissue shrinkage caused by different histological fixatives using magnetic resonance and computed tomography imaging Wehrl HF, Bezrukov I, Wiehr S, Lehnhoff M, Fuchs K, Mannheim JG, Quintanilla-Martinez L, Kohlhofer U, Kneilling M, Pichler BJ, Sauter AW. Histol Histopathol. 2015 May;30(5):601-13. Janus kinase 3 regulates renal 25-hydroxyvitamin D 1α-hydroxylase expression, calcitriol formation, and phosphate metabolism Umbach AT, Zhang B, Daniel C, Fajol A, Velic A, Hosseinzadeh Z, Bhavsar SK, Bock CT, Kandolf R, Pichler BJ, Amann KU, Föller M, Lang F. Kidney Int. 2015 Apr;87(4):728-37. Checkpoint kinase Chk2 controls renal Cyp27b1 expression, calcitriol formation, and calcium-phosphate metabolism Fahkri H, Zhang B, Fajol A, Hernando N, Elvira B, Mannheim JG, Pichler BJ, Daniel C, Amann K, Hirao A, Haight J, Mak TW, Lang F, Föller M. Pflugers Arch. 2015 Sep;467(9):1871-80. Identification of RIP1 as a critical mediator of Smac mimetic-mediated sensitization of glioblastoma cells for Drozitumab-induced apoptosis Cristofanon S, Abhari BA, Krueger M, Tchoghandjian A, Momma S, Calaminus C, Vucic D, Pichler BJ, Fulda S. Cell Death Dis. 2015 Apr 16;6:e1724. Regeneration of Degenerated Urinary Sphincter Muscles: Improved Stem Cell-Based Therapies and Novel Imaging Technologies Amend B, Vaegler M, Fuchs K, Mannheim JG, Will S, Kramer U, Hart ML, Feitz W, Chapple C, Stenzl A, Aicher WK. Cell Transplant. 2015;24(11):2171-83. Inhibition of the PI3K pathway with buparlisib (BKM120) is a suitable strategy to overcome therapy resistance in melanoma-derived brain metastasis in vitro and in vivo Niessner H, Schmitz J, Schmid A, Sinnberg T, Tabatabai G, Weide B, Garbe C, Quintanilla-Fend L, Beissert S, Kulms D, Pichler B, Meier F. Exp Dermatol. 2015;24(3):E32. Segmentation-based attenuation correction in positron emission tomography/magnetic resonance: erroneous tissue identification and its impact on positron emission tomography interpretation Brendle C, Schmidt H, Oergel A, Bezrukov I, Mueller M, Schraml C, Pfannenberg C, la Fougère C, Nikolaou K, Schwenzer N. Invest Radiol. 2015 May;50(5):339-46. Quantitative Evaluation of Segmentation- and Atlas-Based Attenuation Correction for PET/MR on Pediatric Patients Bezrukov I, Schmidt H, Gatidis S, Mantlik F, Schäfer JF, Schwenzer N, Pichler BJ. J Nucl Med. 2015 Jul;56(7):1067-74. Shine-Through in PET/MR Imaging: Effects of the Magnetic Field on Positron Range and Subsequent Image Artifacts Kolb A, Sauter AW, Eriksson L, Vandenbrouke A, Liu CC, Levin C, Pichler BJ, Rafecas M. J Nucl Med. 2015 Jun;56(6):951-4. Quantification of β-Amyloidosis and rCBF with Dedicated PET, 7 T MR Imaging, and High-Resolution Microscopic MR Imaging at 16.4 T in APP23 Mice Maier FC, Keller MD, Bukala D, Bender B, Mannheim JG, Brereton IM, Galloway GJ, Pichler BJ. J Nucl Med. 2015 Oct;56(10):1593-9. Combined PET/MR: The Real Work Has Just Started Bailey DL, Antoch G, Bartenstein P, Barthel H, Beer AJ, Bisdas S, Bluemke DA, Boellaard R, Claussen CD, Franzius C, Hacker M, Hricak H, la Fougère C, Gückel B, Nekolla SG, Pichler BJ, Purz S, Quick HH, Sabri O, Sattler B, Schäfer J, Schmidt H, et al. Mol Imaging Biol. 2015 Jun;17(3):297-312. Combined PET/MRI: Multi-modality Multi-parametric Imaging Is Here Bailey DL, Pichler BJ, Gückel B, Barthel H, Beer AJ, Bremerich J, Czernin J, Drzezga A, Franzius C, Goh V, Hartenbach M, Iida H, Kjaer A, la Fougère C, Ladefoged CN, Law I, Nikolaou K, Quick HH, Sabri O, Schäfer J, Schäfers M, Wehrl HF, Beyer T. Mol Imaging Biol. 2015 Oct;17(5):595-608. Combined unsupervised-supervised classification of multiparametric PET/MRI data: application to prostate cancer Gatidis S, Scharpf M, Martirosian P, Bezrukov I, Küstner T, Hennenlotter J, Kruck S, Kaufmann S, Schraml C, la Fougère C, Schwenzer NF, Schmidt H. NMR Biomed. 2015 Jul;28(7):914-22. Cancer-targeted IL-12 controls human rhabdomyosarcoma by senescence induction and myogenic differentiation. Oncoimmunology Schilbach K, Alkhaled M, Welker C, Eckert F, Blank G, Ziegler H, Sterk M, Müller F, Sonntag K, Wieder T, Braumüller H, Schmitt J, Eyrich M, Schleicher S, Seitz C, Erbacher A, Pichler BJ, Müller H, Tighe R, Lim A, Gillies SD, Strittmatter W, et al. Oncoimmunology. 2015 Mar 19;4(7):e1014760. A Comparative pO2 Probe and [18F]-Fluoro-Azomycinarabino-Furanoside ([18F]FAZA) PET Study Reveals Anesthesia-Induced Impairment of Oxygenation and Perfusion in Tumor and Muscle Mahling M, Fuchs K, Thaiss WM, Maier FC, Feger M, Bukala D, Harant M, Eichner M, Reutershan J, Lang F, Reischl G, Pichler BJ, Kneilling M. PLoS One. 2015 Apr 22;10(4):e0124665. Olesoxime suppresses calpain activation and mutant huntingtin fragmentation in the BACHD rat Clemens LE, Weber JJ, Wlodkowski TT, Yu-Taeger L, Michaud M, Calaminus C, Eckert SH, Gaca J, Weiss A, Magg JC, Jansson EK, Eckert GP, Pichler BJ, Bordet T, Pruss RM, Riess O, Nguyen HP. Brain. 2015 Dec;138(Pt 12):3632-53. Endothelial depletion of murine SRF/MRTF provokes intracerebral hemorrhagic stroke Weinl C, Castaneda Vega S, Riehle H, Stritt C, Calaminus C, Wolburg H, Mauel S, Breithaupt A, Gruber AD, Wasylyk B, Olson EN, Adams RH, Pichler BJ, Nordheim A. Proc Natl Acad Sci U S A. 2015 Aug 11;112(32):9914-9. Cholesterol Modification of p40-Specific Small Interfering RNA Enables Therapeutic Targeting of Dendritic Cells Brück J, Pascolo S, Fuchs K, Kellerer C, Glocova I, Geisel J, Dengler K, Yazdi AS, Röcken M, Ghoreschi K. J Immunol. 2015 Sep 1;195(5):2216-23. A data driven method for estimation of Bavail and appKD using a single injection protocol with [11C]raclopride in the mouse Wimberley CJ, Fischer K, Reilhac A, Pichler BJ, Gregoire MC. Neuroimage. 2014 Oct. 99:365-76 Apical constriction: location and dimensions in molars-a micro-computed tomography study ElAyouti A, Hülber-J M, Judenhofer MS, Connert T, Mannheim JG, Löst C, Pichler BJ, von Ohle C. J Endod. 2014 Aug. 40(8):1095-9. Implications of glycoprotein VI for theranostics Gawaz M, Vogel S, Pfannenberg C, Pichler B, Langer H, Bigalke B. Thromb Haemost. 2014 Jul 3;112(1):26-31. In vivo optical imaging of matrix metalloproteinase activity detects acute and chronic contact hypersensitivity reactions and enables monitoring of the antiinflammatory effects of N-acetylcysteine Schwenck J, Griessinger CM, Fuchs K, Bukala D, Bauer N, Eichner M, Röcken M, Pichler BJ, Kneilling M. Mol Imaging. 2014;13. In Vivo Tracking of Th1 Cells by PET Reveals Quantitative and Temporal Distribution and Specific Homing in Lymphatic Tissue Griessinger CM, Kehlbach R, Bukala D, Wiehr S, Bantleon R, Cay F, Schmid A, Braumüller H, Fehrenbacher B, Schaller M, Eichner M, Sutcliffe JL, Ehrlichmann W, Eibl O, Reischl G, Cherry SR, Röcken M, Pichler BJ, Kneilling M. J Nucl Med. 2014 Feb. 55(2):301-7 Longitudinal PET-MRI reveals β-amyloid deposition and rCBF dynamics and connects vascular amyloidosis to quantitative loss of perfusion Maier FC, Wehrl HF, Schmid AM, Mannheim JG, Wiehr S, Lerdkrai C, Calaminus C, Stahlschmidt A, Ye L, Burnet M, Stiller D, Sabri O, Reischl G, Staufenbiel M, Garaschuk O, Jucker M, Pichler BJ. Nat Med. 2014 Dec. 20(12):1485-92. On the Quantification Accuracy, Homogeneity, and Stability of Simultaneous Positron Emission Tomography/Magnetic Resonance Imaging Systems Schmidt H, Schwenzer NF, Bezrukov I, Mantlik F, Kolb A, Kupferschläger J, Pichler BJ. Invest Radiol. 2014 Jun. 49(6):373-81 PET/MR Imaging and Optical Imaging of Metastatic Rhabdomyosarcoma in Mice Armeanu-Ebinger S, Griessinger CM, Herrmann D, Fuchs J, Kneilling M, Pichler BJ, Seitz G. J Nucl Med. 2014 Sep. 55(9):1545-51 Pharmacokinetics and PET imaging properties of two recombinant anti-PSMA antibody fragments in comparison to their parental antibody Wiehr S, Bühler P, Gierschner D, Wolf P, Rolle AM, Kesenheimer C, Pichler BJ, Elsässer-Beile U. Prostate. 2014 May. 74(7):743-55 Preclinical and Translational PET/MR Imaging Wehrl HF, Wiehr S, Divine MR, Gatidis S, Gullberg GT, Maier FC, Rolle AM, Schwenck J, Thaiss WM, Pichler BJ. J Nucl Med. 2014 May 15. 55(Supplement 2):11S-18S. Principles of PET/MR Imaging Disselhorst JA, Bezrukov I, Kolb A, Parl C, Pichler BJ. J Nucl Med. 2014 May 12. 55(Supplement 2):2S-10S. Quantitative Correlation at the Molecular Level of Tumor Response to Docetaxel by Multimodal Diffusion-Weighted Magnetic Resonance Imaging and [18F]FDG/[18F]FLT Positron Emission Tomography Honndorf VS, Schmidt H, Wehrl HF, Wiehr S, Ehrlichmann W, Quintanilla-Martinez L, Barjat H, Ricketts SA, Pichler BJ. Mol Imaging. 2014 Nov 1. 13(0):1-12. Radioimmunoimaging of liver metastases with PET using a 64Cu-labeled CEA antibody in transgenic mice Nittka S, Krueger MA, Shively JE, Boll H, Brockmann MA, Doyon F, Pichler BJ, Neumaier M. PLoS One. 2014 Sep 16. 9(9):e106921. Simulation-based optimisation of the PET data processing for Partial Saturation Approach protocols Wimberley C, Angelis G, Boisson F, Callaghan P, Fischer K, Pichler B, Meikle SR, Grégoire MC, Reilhac A. Neuroimage. 2014 Aug 15. 97:29-40. Up-Regulation of Hepatic Alpha-2-HS-Glycoprotein Transcription by Testosterone via Androgen Receptor Activation Voelkl J, Pakladok T, Lin Y, Viereck R, Lebedeva A, Kukuk D, Pichler BJ, Alesutan I, Lang F. Cell Physiol Biochem. 2014 Jun 27. 33(6):1911-1920. Development of a novel depth of interaction PET detector using highly multiplexed G-APD cross-strip encoding Kolb A, Parl C, Mantlik F, Liu CC, Lorenz E, Renker D, Pichler BJ. Med Phys. 2014 Aug. 41(8):081916. Evaluation of positron emission tomographic tracers for imaging of papillomavirus-induced tumors in rabbits Probst S, Wiehr S, Mantlik F, Schmidt H, Kolb A, Münch P, Delcuratolo M, Stubenrauch F, Pichler BJ, Iftner T. Mol Imaging. 2014 Jan-Feb. 13(1). Assessment of rodent brain activity using combined [15O]H2O-PET and BOLD-fMRI Wehrl HF, Martirosian P, Schick F, Reischl G, Pichler BJ. Neuroimage. 2014 Apr 1. 89:271-9 Combined PET/MR: Where Are We Now? Summary Report of the Second International Workshop on PET/MR Imaging April 8-12, 2013, Tubingen, Germany Bailey DL, Barthel H, Beuthin-Baumann B, Beyer T, Bisdas S, Boellaard R, Czernin J, Drzezga A, Ernemann U, Franzius C, Gückel B, Handgretinger R, Hartenbach M, Hellwig D, Nadel H, Nekolla SG, Pfluger T, Pichler BJ, Quick HH, Sabri O, Sattler B, et al. Mol Imaging Biol. 2014 Jun. 16(3):295-310. A novel transgenic rat model for spinocerebellar ataxia type 17 recapitulates neuropathological changes and supplies in vivo imaging biomarkers Kelp A, Koeppen AH, Petrasch-Parwez E, Calaminus C, Bauer C, Portal E, Yu-Taeger L, Pichler B, Bauer P, Riess O, Nguyen HP. J Neurosci. 2013 May 22. 33(21):9068-81. A progressive dopaminergic phenotype associated with neurotoxic conversion of α-synuclein in BAC-transgenic rats Nuber S, Harmuth F, Kohl Z, Adame A, Trejo M, Schönig K, Zimmermann F, Bauer C, Casadei N, Giel C, Calaminus C, Pichler BJ, Jensen PH, Müller CP, Amato D, Kornhuber J, Teismann P, Yamakado H, Takahashi R, Winkler J, Masliah E, Riess O Brain 2013 136(2): 412-432 Feasibility of Sequential PET/MRI Using a State-of-the-Art Small Animal PET and a 1 T Benchtop MRI Schmid A, Schmitz J, Mannheim JG, Maier FC, Fuchs K, Wehrl HF, Pichler BJ Mol Imaging Biol. 2013 Apr. 15(2):155-65. Imaging Findings and Therapy Response Monitoring in Chronic Sclerodermatous Graft-Versus-Host Disease: Preliminary Data of a Simultaneous PET/MRI Approach Sauter AW, Schmidt H, Mantlik F, Kolb A, Federmann B, Pfannenberg C, Reimold M, Pichler BJ, Bethge W, Horger MS. Clin Nucl Med. 2013 Aug. 38(8):e309-17 Impact of Anesthetics On 3'-[18F]Fluoro-3'-Deoxythymidine ([18F]FLT) Uptake in Animal Models of Cancer and Inflammation Fuchs K, Kukuk D, Mahling M, Quintanilla-Martinez L, Reischl G, Reutershan J, Lang F, Röcken M, Pichler BJ, Kneilling M. Mol Imaging. 2013 Aug 1. 12(5):277-87. In Vivo Imaging of Cell Proliferation Enables the Detection of the Extent of Experimental Rheumatoid Arthritis by 3'-Deoxy-3'-18F-Fluorothymidine and Small-Animal PET Fuchs K, Kohlhofer U, Quintanilla-Martinez L, Lamparter D, Kötter I, Reischl G, Röcken M, Pichler BJ, Kneilling M. J Nucl Med. 2013 Jan. 54(1):151-8 MR-Based Attenuation Correction Methods for Improved PET Quantification in Lesions Within Bone and Susceptibility Artifact Regions Bezrukov I, Schmidt H, Mantlik F, Schwenzer N, Brendle C, Schölkopf B, Pichler BJ. J Nucl Med. 2013 Oct. 54(10):1768-74 MR-Based PET Attenuation Correction for PET/MR Imaging Bezrukov I, Mantlik F, Schmidt H, Schölkopf B, Pichler BJ. Semin Nucl Med. 2013 Jan. 43(1):45-59. Multimodal Elucidation of Choline Metabolism in a Murine Glioma Model using Magnetic Resonance Spectroscopy and 11C-choline Positron Emission Tomography Wehrl HF, Schwab J, Hasenbach K, Reischl G, Tabatabai G, Quintanilla-Martinez L, Jiru F, Chughtai K, Kiss A, Cay F, Bukala D, Heeren RM, Pichler BJ, Sauter AW. Cancer Res. 2013 Mar 1. 73(5):1470-80. Non-invasive Monitoring of Pancreatic Tumor Progression in the RIP1-Tag2 Mouse by Magnetic Resonance Imaging Schmid A, Braumüller H, Wehrl HF, Röcken M, Pichler BJ Mol Imaging Biol. 2013 Apr. 15(2):186-93. Preclinical Evaluation of a Novel c-Met Inhibitor in a Gastric Cancer Xenograft Model Using Small Animal PET Wiehr S, von Ahsen O, Röse L, Mueller A, Mannheim JG, Honndorf V, Kukuk D, Reischl G, Pichler BJ. Mol Imaging Biol. 2013 Apr. 15(2):203-11. Selective poisoning of Ctnnb1-mutated hepatoma cells in mouse liver tumors by a single application of acetaminophen Singh Y, Braeuning A, Schmid A, Pichler BJ, Schwarz M. Arch Toxicol. 2013 Aug. 87(8):1595-607 Simultaneous PET/MR reveals Brain Function in Activated and Resting State on Metabolic, Hemodynamic and Multiple Temporal Scales Wehrl HF, Hossain M, Lankes K, Liu C-C, Bezrukov I, Martirosian P, Schick F, Reischl G, Pichler BJ. Nat. Med. 2013 Sep. 19(9): 1184-9 SOX2 Expression Associates with Stem Cell State in Human Ovarian Carcinoma Bareiss PM, Paczulla A, Wang H, Schairer R, Wiehr S, Kohlhofer U, Rothfuss OC, Fischer A, Perner S, Staebler A, Wallwiener D, Fend F, Fehm T, Pichler B, Kanz L, Quintanilla-Martinez L, Schulze-Osthoff K, Essmann F, Lengerke C. Cancer Res. 2013 Sep 1. 73(17):5544-55 Summary Report of the First International Workshop on PET/MR Imaging, March 19-23, 2012, Tübingen, Germany Bailey DL, Barthel H, Beyer T, Boellaard R, Gückel B, Hellwig D, Herzog H, Pichler BJ, Quick HH, Sabri O, Scheffler K, Schlemmer HP, Schwenzer NF, Wehrl HF. Mol Imaging Biol. 2013 Aug. 15(4):361-71 6-Hydroxydopamine leads to T2 hyperintensity, decreased claudin-3 immunoreactivity and altered aquaporin 4 expression in the striatum Wachter B, Schürger S, Schmid A, Gröger A, Sadler R, Speidel A, Rolinger J, Pichler BJ, Berg D, Wagner HJ, von Ameln-Mayerhofer A, Küppers E. Behav Brain Res. 2012 Jun 15;232(1):148-58. A Novel BACHD Transgenic Rat Exhibits Characteristic Neuropathological Features of Huntington Disease Yu-Taeger L, Petrasch-Parwez E, Osmand AP, Redensek A, Metzger S, Clemens LE, Park L, Howland D, Calaminus C, Gu X, Pichler B, Yang XW, Riess O, Nguyen HP J Neurosci. 2012 Oct 31;32(44):15426-38. An Evaluation of 2-deoxy-2-[(18)F]Fluoro-D-Glucose and 3'-deoxy-3'-[(18)F]-Fluorothymidine Uptake in Human Tumor Xenograft Models H. Keen, B. Pichler, D. Kukuk, O. Duchamp, O. Raguin, A. Shannon, N. Whalley, V. Jacobs, J. Bales, N. Gingles, S.A. Ricketts, S.R. Wedge Mol Imaging Biol. 2012 Jun;14(3):355-65. Enhanced FGF23 Serum Concentrations and Phosphaturia in Gene Targeted Mice Expressing WNK-Resistant Spak Pathare G, Föller M, Michael D, Walker B, Hierlmeier M, Mannheim JG, Pichler BJ, Lang F Kidney Blood Press Res. 2012;36(1):355-64. Ex vivo imaging of injured arteries in rabbits using fluorescence-labelled glycoprotein VI-Fc B. Bigalke, S. Lindemann, T. Schönberger, I. Pohlmeyer, A. Chiribiri, A. Schuster, R.M. Botnar, C.M. Griessinger, B.J. Pichler, M. Gawaz Platelets. 2012;23(1):1-6. Generation of a novel rodent model for DYT1 dystonia Grundmann K, Glöckle N, Martella G, Sciamanna G, Hauser TK, Yu L, Castaneda S, Pichler B, Fehrenbacher B, Schaller M, Nuscher B, Haass C, Hettich J, Yue Z, Nguyen HP, Pisani A, Riess O, Ott T. Neurobiol Dis. 2012 Jul;47(1):61-74. Imaging DA release in a rat model of L-DOPA-induced dyskinesias: A longitudinal in vivo PET investigation of the antidyskinetic effect of MDMA Lettfuss NY, Fischer K, Sossi V, Pichler BJ, von Ameln-Mayerhofer A Neuroimage. 2012 Oct 15;63(1):423-33. In vivo quantification of dopamine transporters in mice with unilateral 6-OHDA lesions using [(11)C]methylphenidate and PET K. Fischer, V. Sossi, A. von Ameln-Mayerhofer, G. Reischl, B.J. Pichler Neuroimage. 2012 Feb 1;59(3):2413-22. Monitoring the glioma tropism of bone marrow-derived progenitor cells by 2-photon laser scanning microscopy and positron emission tomography K. Hasenbach, S. Wiehr, C. Herrmann, J. Mannheim, F. Cay, G. von Kürthy, T. Bolmont, S.A. Grathwohl, M. Weller, C. Lengerke, B.J. Pichler, G. Tabatabai Neuro Oncol. 2012 Apr;14(4):471-81. Oxygen Breathing Affects 3'-Deoxy-3'-18F-Fluorothymidine Uptake in Mouse Models of Arthritis and Cancer Fuchs K, Kukuk D, Reischl G, Föller M, Eichner M, Reutershan J, Lang F, Röcken M, Pichler BJ, Kneilling M. J Nucl Med. 2012 May;53(5):823-30. Quantification accuracy and partial volume effect in dependence of the attenuation correction of a state-of-the-art small animal PET scanner Mannheim JG, Judenhofer MS, Schmid A, Tillmanns J, Stiller D, Sossi V, Pichler BJ Phys Med Biol. 2012 Jun 21;57(12):3981-93. Quantitative Analysis of the Growth Kinetics of Chemically-Induced Mouse Liver Tumors by Magnetic Resonance Imaging A. Schmid, B. Rignall, B.J. Pichler, M. Schwarz Toxicol Sci. 2012 Mar;126(1):52-9. Sgk1 sensitivity of Na(+)/H (+) exchanger activity and cardiac remodeling following pressure overload J. Voelkl, Y. Lin, I. Alesutan,M.S. Ahmed, V. Pasham, S. Mia, S. Gu, M. Feger, A. Saxena, B. Metzler, D. Kuhl, B.J. Pichler, F. Lang Basic Res Cardiol. 2012 Mar;107(2):236. Simultaneous PET/MR imaging of the brain: feasibility of cerebral blood flow measurements with FAIR-TrueFISP arterial spin labeling MRI Stegger L, Martirosian P, Schwenzer N, Bisdas S, Kolb A, Pfannenberg C, Claussen CD, Pichler B, Schick F, Boss A Acta Radiol. 2012 Nov 1;53(9):1066-72. Technical performance evaluation of a human brain PET/MRI system Kolb A, Wehrl HF, Hofmann M, Judenhofer MS, Eriksson L, Ladebeck R, Lichy MP, Byars L, Michel C, Schlemmer HP, Schmand M, Claussen CD, Sossi V, Pichler BJ Eur Radiol. 2012 Aug;22(8):1776-88. Unfavorable consequences of chronic cardiac HIF-1α stabilization M. Hölscher, K. Schäfer, S. Krull, K. Farhat, A. Hesse, M. Silter, Y. Lin, B.J. Pichler, P. Thistlethwaite, A. El Armouche, L.S. Maier, D.M. Katschinski, A. Zieseniss Cardiovasc Res. 2012 Apr 1;94(1):77-86. [(68)Ga]NODAGA-RGD for imaging α(v)β (3) integrin expression P.A. Knetsch, M. Petrik, C.M. Griessinger, C. Rangger, M. Fani, C. Kesenheimer, E. von Guggenberg, B.J. Pichler, I. Virgolini, C. Decristoforo, R. Haubner Eur J Nucl Med Mol Imaging. 2011 Jul;38(7):1303-12. Assessment of MR compatibility of a PET insert developed for simultaneous multiparametric PET/MR imaging on an animal system operating at 7 T H.F. Wehrl, M.S. Judenhofer, A. Thielscher, P. Martirosian, F. Schick, B.J. Pichler Magn Reson Med. 2011 Jan;65(1):269-79. Assessment of PET Tracer Uptake in Hormone-Independent and Hormone-Dependent Xenograft Prostate Cancer Mouse Models D. Kukuk, G. Reischl, O. Raguin, S. Wiehr, M.S. Judenhofer, C. Calaminus, V.S. Honndorf, L. Quintanilla-Martinez, T. Schönberger, O. Duchamp, H.J. Machulla, B.J. Pichler J Nucl Med. 2011 Oct;52(10):1654-63. Decreased bone density and increased phosphaturia in gene-targeted mice lacking functional serum- and glucocorticoid-inducible kinase 3 M. Bhandaru, D.S. Kempe, A. Rotte, P. Capuano, G. Pathare, M. Sopjani, I. Alesutan, L. Tyan, D.Y. Huang, B. Siraskar, M.S. Judenhofer, G. Stange, B.J. Pichler, J. Biber, L. Quintanilla-Martinez, C.A. Wagner, D. Pearce, M. Föller, F. Lang Kidney Int. 2011 Jul;80(1):61-7. Feasibility of simultaneous PET/MR imaging in the head and upper neck area A. Boss, L. Stegger, S. Bisdas, A. Kolb, N. Schwenzer, M. Pfister, C.D. Claussen, B.J. Pichler, C. Pfannenberg Eur Radiol. 2011 Jul;21(7):1439-46. Imaging of injured and atherosclerotic arteries in mice using fluorescence-labeled glycoprotein VI-Fc B. Bigalke, I. Pohlmeyer, T. Schönberger, C.M. Griessinger, M. Ungerer, R.M. Botnar, B.J. Pichler, M. Gawaz Eur J Radiol. 2011 Aug;79(2):e63-9. Letter to the editor re: molecular imaging in oncology: the acceptance of PET/CT and the emergence of MR/PET imaging A. Sauter, A. Kolb, M. Soekler, M. Reimold, N. Schwenzer, C. Pfannenberg, C. Claussen, B. Pichler, M. Horger Eur Radiol. 2011 Aug;21(8):1709-12. MRI-Based Attenuation Correction for Whole-Body PET/MRI: Quantitative Evaluation of Segmentation- and Atlas-Based Methods M. Hofmann, I. Bezrukov, F. Mantlik, P. Aschoff, F. Steinke, T. Beyer, B.J. Pichler, B. Schölkopf J Nucl Med. 2011 Sep;52(9):1392-9. Noninvasive nuclear imaging enables the in vivo quantification of striatal dopamine receptor expression and raclopride affinity in mice K. Fischer, V. Sossi, A. Schmid, M. Thunemann, F.C. Maier, M.S. Judenhofer, J.G. Mannheim, G. Reischl, B.J. Pichler J Nucl Med. 2011 Jul;52(7):1133-41. PKB/SGK-Resistant GSK3 Enhances Phosphaturia and Calciuria M. Föller, D.S. Kempe, K.M. Boini, G. Pathare, B. Siraskar, P. Capuano, I. Alesutan, M. Sopjani, G. Stange, N. Mohebbi, M. Bhandaru, T.F. Ackermann, M.S. Judenhofer, B.J. Pichler, J. Biber, C.A. Wagner, F. Lang J Am Soc Nephrol. 2011 May;22(5):873-80. Simultaneous (68)Ga-DOTATOC-PET/MRI for IMRT Treatment Planning for Meningioma: First Experience D. Thorwarth, G. Henke, A.C. Müller, M. Reimold, T. Beyer, A. Boss, A. Kolb, B. Pichler, C. Pfannenberg Int J Radiat Oncol Biol Phys. 2011 Sep 1;81(1):277-83. The effect of patient positioning aids on PET quantification in PET/MR imaging F. Mantlik, M. Hofmann, M.K. Werner, A. Sauter, J. Kupferschläger, B. Schölkopf, B.J. Pichler, T. Beyer Eur J Nucl Med Mol Imaging. 2011 May;38(5):920-9. Akt2/PKBbeta-sensitive regulation of renal phosphate transport D.S. Kempe, T.F. Ackermann, K.M. Boini, F. Klaus, A.T. Umbach, M. Dërmaku-Sopjani, M.S. Judenhofer, B.J. Pichler, P. Capuano, G. Stange, C.A. Wagner, M.J. Birnbaum, D. Pearce, M. Föller, F. Lang Acta Physiol (Oxf). 2010 Sep;200(1):75-85. Combined PET/MR Imaging - Technology and Applications H. F. Wehrl, A. W. Sauter, M. S. Judenhofer, B.J. Pichler Technol Cancer Res Treat. 2010 Feb;9(1):5-20. Combined PET/MRI: one step further in multimodality imaging A.W. Sauter, H.F. Wehrl, A. Kolb, M.S. Judenhofer, B.J. Pichler Trends Mol Med. 2010 Nov;16(11):508-15. Diffusion tensor imaging in a human PET/MR hybrid system A. Boss, A. Kolb, M. Hofmann, S. Bisdas, T. Nägele, U. Ernemann, L. Stegger, C. Rossi, H.P. Schlemmer, C. Pfannenberg, M. Reimold, C.D. Claussen, B.J. Pichler, U. Klose Invest Radiol. 2010 May;45(5):270-4. Effects of in vitro exposure of Echinococcus multilocularis metacestodes to cytostatic drugs on in vivo growth and proliferation of the parasite C. Hübner, S. Wiehr, L. Kocherscheidt, H. Wehrl, B.J. Pichler, A. Schmid, P. Kern, P.T. Soboslay Parasitol Res. 2010 Jul;107(2):459-63. Evaluation of Geiger-mode APDs for PET block detector designs A. Kolb, E. Lorenz, M.S. Judenhofer, D. Renker, K. Lankes, B.J. Pichler Phys Med Biol. 2010 Apr 7;55(7):1815-32. High-resolution animal PET imaging of prostate cancer xenografts with three different (64)Cu-labeled antibodies against native cell-adherent PSMA K. Alt, S. Wiehr, W. Ehrlichmann, G. Reischl, P. Wolf, B.J. Pichler, U. Elsässer-Beile, P. Bühler Prostate. 2010 Sep 15;70(13):1413-21. Hybrid PET/MRI of intracranial masses: initial experiences and comparison to PET/CT A. Boss, S. Bisdas, A. Kolb, M. Hofmann, U. Ernemann, C.D. Claussen, C. Pfannenberg, B.J. Pichler, M. Reimold, L. Stegger J Nucl Med. 2010 Aug;51(8):1198-205. Isochronous assessment of cardiac metabolism and function in mice using hybrid PET/MRI K. Büscher, M.S. Judenhofer, M.T. Kuhlmann, S. Hermann, H.F. Wehrl, K.P. Schäfers, M. Schäfers, B.J. Pichler, L. Stegger J Nucl Med. 2010 Aug;51(8):1277-84. Para-phenylenediamine-specific lymphocyte activation test: a sensitive in vitro assay to detect para-phenylenediamine sensitization in patients with severe allergic reactions M. Kneilling, U. Caroli, C. Grimmel, J. Fischer, M. Eichner, T. Wieder, F.C. Maier, M. Röcken, T. Biedermann Exp Dermatol. 2010 May;19(5):435-41. PET/MRI: Paving the Way for the Next Generation of Clinical Multimodality Imaging Applications B.J. Pichler, A. Kolb, T. Nägele, H.P Schlemmer J Nucl Med. 2010 Mar;51(3):333-6. Phosphoglycerate kinase 1 promoting tumor progression and metastasis in gastric cancer - detected in a tumor mouse model using positron emission tomography/magnetic resonance imaging D. Zieker, I. Königsrainer, J. Weinreich, S. Beckert, J. Glatzle, K. Nieselt, S. Bühler, M. Löffler, J. Gaedcke, H. Northoff, J.G. Mannheim, S. Wiehr, B.J. Pichler, C. von Weyhern, B.L. Brücher, A. Königsrainer Cell Physiol Biochem. 2010;26(2):147-54. Switching on the Lights for Real-Time Multimodality Tumor Neuroimaging: The Integrated Positron-Emission Tomography/MR Imaging System S. Bisdas, T. Nägele, H.P. Schlemmer, A. Boss, C.D. Claussen, B. Pichler, U. Ernemann AJNR Am J Neuroradiol. 2010 Apr;31(4):610-4. Transgenic overexpression of the alpha-synuclein interacting protein synphilin-1 leads to behavioral and neuropathological alterations in mice S. Nuber, T. Franck, H. Wolburg, U. Schumann, N. Casadei, K. Fischer, C. Calaminus, B.J. Pichler, S. Chanarat, P. Teismann, J.B. Schulz, A.R. Luft, J. Tomiuk, J. Wilbertz, A. Bornemann, R. Krüger, O. Riess Neurogenetics. 2010 Feb;11(1):107-20. A decade of combined imaging: from a PET attached to a CT to a PET inside an MR T. Beyer, B.J. Pichler Eur J Nucl Med Mol Imaging. 2009 Mar;36 Suppl 1:S1-2. Direct Crosstalk between Mast Cell-TNF and TNFR1-expressing Endothelia Mediates Local Tissue Inflammation M. Kneilling , R. Mailhammer, L. Hültner, T. Schönberger, K. Fuchs, M. Schaller, D. Bukala, S. Massberg, C.A. Sander, M. Eichner, K.L. Maier, R. Hallmann, B.J. Pichler, R. Haubner, M. Gawaz, K. Pfeffer, T. Biedermann, M. Röcken Blood. 2009 Aug 20;114(8):1696-706. Molecular Imaging H.P Schlemmer, R. Bares, C.D. Claussen, B.J. Pichler Dtsch Med Wochenschr. 2009 May;134(19):1000-5. New perspectives on bone marrow contrast agents and molecular imaging H.E. Daldrup-Link, A. Mohanty, C. Cuenod, B. Pichler, T. Link Semin Musculoskelet Radiol. 2009 Jun;13(2):145-56. PET imaging of prostate cancer xenografts with a highly specific antibody against the postate specific membrane antigen U. Elsässer-Beile, G. Reischl. S. Wiehr, P. Bühler, P. Wolf, K. Alt, J. Shively, M.S. Judenhofer, H.J. Machulla, B.J. Pichler J Nucl Med. 2009 Apr;50(4):606-11. Pre-clinical PET/MR: technological advances and new perspectives in biomedical research H.F. Wehrl, M.S. Judenhofer, S. Wiehr, B.J. Pichler Eur J Nucl Med Mol Imaging. 2009 Mar;36 Suppl 1:S56-68. Towards quantitative PET/MRI: a review of MR-based attenuation correction techniques M. Hofmann, B.J. Pichler, B. Schölkopf, T. Beyer Eur J Nucl Med Mol Imaging. 2009 Mar;36 Suppl 1:S93-104. An integrated MR/PET system: prospective applications H-P.W. Schlemmer, B.J. Pichler, R. Krieg, W.D. Heiss Abdom Imaging. 2009 Nov;34(6):668-74. Anemia and splenomegaly in cGKI-deficient mice M. Föller, S. Feil, K. Ghoreschi, S. Koka, A. Gerling, M. Thunemann, F. Hofmann, B. Schuler, J. Vogel, B. Pichler, R.S. Kasinathan, J.P. Nicolay, S.M. Huber, F. Lang, R. Feil Proc Natl Acad Sci U S A. 2008 May 6;105(18):6771-6. Cell tracking with optical imaging E.J. Sutton, T.D. Henning, B.J. Pichler, C. Bremer, H.E. Daldrup-Link Eur Radiol. 2008 Oct;18(10):2021-32. Latest advances in molecular imaging instrumentation B.J. Pichler, H.F. Wehrl, M.S. Judenhofer J Nucl Med. 2008 Jun;49 Suppl 2:5S-23S. Measurement of T1, T2, and Magnetization Transfer Properties During Embryonic Development at 7 Tesla Using the Chicken Model A. Boss, M. Oppitz, H.F. Wehrl, C. Rossi, M. Feuerstein, C.D. Claussen, U. Drews, B.J. Pichler, F.Schick J Magn Reson Imaging. 2008 Dec;28(6):1510-4. MRI-Based Attenuation Correction for PET/MRI: A Novel Approach Combining Pattern Recognition and Atlas Registration M. Hofmann, F. Steinke, V. Scheel, G. Charpiat, J. Farquhar, P. Aschoff, M. Brady, B. Schölkopf, B.J. Pichler J Nucl Med. 2008 Nov;49(11):1875-83. Neurodegeneration and motor dysfunction in a conditional model of Parkinson's disease Nuber S, Petrasch-Parwez E, Winner B, Winkler J, von Hoersten S, Schmidt T, Boy J, Kuhn M, Nguyen HP, Teismann P, Schulz JB, Neumann M, Pichler BJ, Reischl G, Holzmann C, Schmitt I, Bornemann A, Kuhn W, Zimmermann F, Servadio A, Riess O. J Neurosci. 2008 Mar 5;28(10):2471-84. PET/MRI hybrid imaging: devices and initial results B.J. Pichler, M.S. Judenhofer, H.F. Wehrl Eur Radiol. 2008 Jun;18(6):1077-86. Platelet GPVI binds to collagenous structures in the core region of human atheromatous plaque and is critical for atheroprogression in vivo C. Schulz, S. Penz, C. Hoffmann, H. Langer, A. Gillitzer, S. Schneider, R. Brandl, S. Seidl, S. Massberg, B. Pichler, E. Kremmer, K. Stellos, T. Schönberger, W. Siess, M. Gawaz Basic Res Cardiol. 2008 Jul;103(4):356-67. Positron emission tomography/magnetic resonance imaging: the next generation of multimodality imaging? B.J. Pichler, H.F. Wehrl, A. Kolb, M.S. Judenhofer Semin Nucl Med. 2008 May;38(3):199-208. Radionuclide imaging: A molecular key to the atherosclerotic plaque H.F. Langer, R. Haubner, B.J. Pichler, M. Gawaz J Am Coll Cardiol. 2008 Jul 1;52(1):1-12. Simultaneous in vivo positron emission tomography and magnetic resonance imaging Catana C, Procissi D, Wu Y, Judenhofer MS, Qi J, Pichler BJ, Jacobs RE, Cherry SR. Proc Natl Acad Sci U S A. 2008 Mar 11;105(10):3705-10. Simultaneous MR/PET Imaging of the Human Brain: Feasibility Study H-P.W. Schlemmer, B.J. Pichler, M. Schmand, Z. Burbar, C. Michel, R. Ladebeck, K. Jattke, D. Townsend, C. Nahmias, P.K. Jacob, W.-D. Heiss, C.D. Claussen Radiology. 2008 Sep;248(3):1028-35. Simultaneous PET/MRI: A new approach for functional and morphological imaging M.S. Judenhofer, H.F. Wehrl, D.F. Newport, C. Catana, S.B. Siegel, M. Becker, A. Thielscher, M. Kneilling, M. Lichy, M. Eichner, K. Klingel, G. Reischl, S. Widmaier, M. Röcken, R.E. Nutt, H.-J. Machulla, K. Uludag, S.R. Cherry, C.D. Claussen, B.J. Pichler Nat Med. 2008 Apr;14(4):459-65. Single and dual energy attenuation correction in PET/CT in the presence of iodine based contrast agents N.S. Rehfeld, B.J. Heismann, J. Kupferschläger, P. Aschoff, G. Christ, A.C. Pfannenberg, B.J. Pichler Med Phys. 2008 May;35(5):1959-69. T cell-mediated help against tumors T. Wieder, H. Braumüller, M. Kneilling, B. Pichler, M. Röcken Cell Cycle. 2008 Oct;7(19):2974-7. The immunoadhesin glycoprotein VI-Fc regulates arterial remodeling after mechanical injury in ApoE-/- mice T. Schönberger, D. Siegel&ndash. Axel, R. Buß. l, S. Richter, M.S. Judenhofer, R. Haubner, G. Reischl, K. Klingel, G. Münch, P. Seizer, B.J. Pichler, M. Gawaz Cardiovasc Res. 2008 Oct 1;80(1):131-7. TNFR1 signaling and IFN-gamma signaling determine whether T cells induce tumor dormancy or promote multistage carcinogenesis N. Müller-Hermelink, H. Braumüller, B. Pichler, T. Wieder, R. Mailhammer, K. Schaak, K. Ghoreschi, A. Yazdi, R. Haubner, C.A. Sander, R. Mocikat, M. Schwaiger, I. Förster, R. Huss, W.A. Weber, M. Kneilling, M. Röcken Cancer Cell. 2008 Jun;13(6):507-18. A splice site mutation in the murine Opa1 gene features pathology of autosomal dominant optic atrophy Alavi MV, Bette S, Schimpf S, Schuettauf F, Schraermeyer U, Wehrl HF, Ruttiger L, Beck SC, Tonagel F, Pichler BJ, Knipper M, Peters T, Laufs J, Wissinger B. Brain. 2007 Apr;130(Pt 4):1029-42. PET/MR images acquired with a compact MR-compatible PET detector in a 7-T magnet Judenhofer MS, Catana C, Swann BK, Siegel SB, Jung WI, Nutt RE, Cherry SR, Claussen CD, Pichler BJ. Radiology. 2007 Sep;244(3):807-14. Severe intestinal obstruction on induced smooth muscle-specific ablation of the transcription factor SRF in adult mice Angstenberger M, Wegener JW, Pichler BJ, Judenhofer MS, Feil S, Alberti S, Feil R, Nordheim A. Gastroenterology. 2007 Dec;133(6):1948-59. Spontaneous cellular uptake of exogenous messenger RNA in vivo is nucleic acid-specific, saturable and ion dependent Probst J, Weide B, Scheel B, Pichler BJ, Hoerr I, Rammensee HG, Pascolo S. Gene Ther. 2007 Aug;14(15):1175-80. Targeted mast cell silencing protects against joint destruction and angiogenesis in experimental arthritis in mice Kneilling M, Hultner L, Pichler BJ, Mailhammer R, Morawietz L, Solomon S, Eichner M, Sabatino J, Biedermann T, Krenn V, Weber WA, Illges H, Haubner R, Rocken M. Arthritis Rheum. 2007 Jun;56(6):1806-16. A hyperspectral fluorescence system for 3D in vivo optical imaging G. Zavattini, S. Vecchi, G. Mitchell, U. Weisser, R.M. Leahy, B.J. Pichler, D.J. Smith, S.R. Cherry Phys Med Biol. 2006 Apr 21;51(8):2029-43. Optical imaging of experimental arthritis using allogeneic leukocytes labelled with a near-infrared fluorescent probe G.H. Simon, H.E. Daldrup-Link, J. Kau, S. Metz, J. Schlegel, G. Piontek, O. Sabarowski, S. Demos, J. Duyster, B.J. Pichler Eur J Nucl Med Mol Imaging. 2006 Sep;33(9):998-1006. Performance test of a LSO-APD detector in a 7 Tesla MRI scanner for simultaneous PET-MR imaging. B.J. Pichler, M.S. Judenhofer, C. Catana, J.H. Walton, M. Kneilling, R.E. Nutt, S.B. Siegel, C.D. Claussen, S.R. Cherry J Nucl Med. 2006 Apr;47(4):639-47. Simultaneous acquisition of multislice PET and MR images: initial results with a MR-compatible PET scanner Catana C, Wu Y, Judenhofer MS, Qi J, Pichler BJ, Cherry SR. J Nucl Med. 2006 Dec;47(12):1968-76. Characterization and readout of MADPET-II detector modules: validation of a unique design concept for high resolution small animal PET D.P. McElroy, W. Pimpl, B.J. Pichler, M. Rafecas, T. Schüler, S.I. Ziegler IEEE. Trans. Nucl. Sci. 2005 Apr 11;52(1):199-204 Evaluation of high performance data acquisition boards for simultaneous sampling of fast signals from PET detectors M.S. Judenhofer, B.J. Pichler, S.R. Cherry Phys Med Biol. 2005 Jan 7;50(1):29-44. Imaging of delayed type hypersensitivity reaction by positron emission tomography and [18F]Galacto-RGD B.J. Pichler, M. Kneilling, R. Haubner, H. Braumüller, M. Schwaiger, M. Röcken, W.A. Weber J Nucl Med. 2005 Jan;46(1):184-9.