2020

2020

• Advancing Biomarker Development Through Convergent Engagement: Summary Report of the 2nd International Danube Symposium on Biomarker Development, Molecular Imaging and Applied Diagnostics; March 14-16, 2018; Vienna, Austria.
  Lim MS, Beyer T, Babayan A, Bergmann M, ..., Mitterhauser M, Pichler BJ, Salih HR, Schibli R, Schulz S, Simecek J, Simon J, Soares MO, Stelzl U, Wadsak W, Zatloukal K, Zeitlinger M, Hacker M
  Mol Imaging Biol. 2020 Feb; 22(1):47-65
• Imaging SERT Availability in a Rat Model of L-DOPA-Induced Dyskinesia.
  Walker M, Kuebler L, Goehring CM, Pichler BJ, Herfert K
  Mol Imaging Biol. 2020 Jun;22(3):634-642.
• Temporal Dynamics of Reactive Oxygen and Nitrogen Species and NF-κB Activation During Acute and Chronic T Cell-Driven Inflammation.
  Schwenck J, Mehling R, Thaiss WM, Kramer D, Menendez IG, Öz HH, Hartl D, Schulze-Osthoff K, Hailfinger S, Ghoreschi K, Quintanilla-Martinez L, Carlsen H, Röcken M, Pichler BJ, Kneilling M
  Mol Imaging Biol. 2020 Jun;22(3):504-514.
• PET/MRI enables simultaneous in vivo quantification of β-cell mass and function.
  Michelotti FC, Bowden G, Küppers A, Joosten L, Maczewsky J, Nischwitz V, Drews G, Maurer A, Gotthardt M, Schmid AM, Pichler BJ
  Theranostics 2020 Jan; 10(1):398-410.
• Cancer immunotherapy is accompanied by distinct metabolic patterns in primary and secondary lymphoid organs observed by non-invasive in vivo 18F-FDG-PET.
  Schwenck J, Schörg B, Fiz F, Sonanini D, Forschner A, Eigentler T, Weide B, Martella M, Gonzalez-Menendez I, Campi C, Sambuceti G, Seith F, Quintanilla-Martinez L, Garbe C, Pfannenberg C, Röcken M, Fougere Cl, Pichler BJ, Kneilling M
  Theranostics 2020 Jan; 10(2):925-937.
• Selective protection of murine cerebral G(i/o)-proteins from inactivation by parenterally injected pertussis toxin.
  Vega SC, Leiss V, Piekorz R, Calaminus C, Pexa K, Vuozzo M, Schmid AM, Devanathan V, Kesenheimer C, Pichler BJ, Beer-Hammer S, Nürnberg B
  J Mol Med 2020 Jan; 98(1): 97-110
• Simultaneous whole-body PET/MRI with integrated multiparametric MRI for primary staging of high-risk prostate cancer.
  Kaufmann S, Kruck S, Gatidis S, Hepp T, Thaiss WM, Hennenlotter J, Schwenck J, Scharpf M, Nikolaou K, Stenzl A, Reischl G, la Fougère C, Bedke J
  World J Urol. 2020 Jan; [Epub ahead of print]
• Circadian rhythm impacts preclinical FDG-PET quantification in the brain, but not in xenograft tumors.
  Krueger MA, Calaminus C, Schmitt J, Pichler BJ
  Sci Rep. 2020 Mar; 10(1): 5587
• Cancer immune control needs senescence induction by interferon-dependent cell cycle regulator pathways in tumours.
  Brenner E, Schörg BF, Ahmetlić F, Wieder T, Hilke FJ, Simon N, Schroeder C, ... ,Quintanilla-Martinez L, Pichler BJ, Kneilling M, Mocikat R, Röcken M
  Nat Commun. 2020 Mar; 11(1): 1335
• 11 C Radiolabeling of anle253b: a Putative PET Tracer for Parkinson's Disease That Binds to α-Synuclein Fibrils in vitro and Crosses the Blood-Brain Barrier.
  Maurer A, Leonov A, Ryazanov S, Herfert K, Kuebler L, Buss S, Schmidt F, Weckbecker D, Linder R, Bender D, Giese A, Pichler BJ, Griesinger C
  ChemMedChem. 2020 Mar; 15(5): 411-415
• The scaffold protein p62 regulates adaptive thermogenesis through ATF2 nuclear target activation.
  Fischer K, Fenzl A, Liu D, ..., Brüning JC, Kneilling M, Maier FC, Othman AE, Pichler BJ, Pramme-Steinwachs I, Sachs S, Scheideler A, Thaiss WM, Uhlenhaut H, Ussar S, Woods SC, Zorn J, Stemmer K, Collins S, Diaz-Meco M, Moscat J, Tschöp MH, Müller TD
  Nat Commun. 2020 May 8; 11(1):2306. doi: 10.1038/s41467-020-16230-8.
• Extensive rewiring of the EGFR network in colorectal cancer cells expressing transforming levels of KRASG13D.
  Kennedy SA, Jarboui MA, Srihari S, Raso C, Bryan K, Dernayka L, Charitou T, Bernal-Llinares M, Herrera-Montavez C, Krstic A, ... Auer M, Horn N, Klose F, Ueffing M, Boldt K, Lynn DJ, Kolch W
  Nat Commun. 2020 Jan 24;11(1):499. doi: 10.1038/s41467-019-14224-9.
• Lactate production precedes inflammatory cell recruitment in arthritic ankles: an imaging study
  Neveu MA, Beziere N, Daniels R, Bouzin C, Comment A, Schwenck J, Fuchs K, Kneilling M, Pichler BJ, Schmid AM
  Mol Imaging Biol. 2020 Jun 8. doi: 10.1007/s11307-020-01510-y. Online ahead of print.
• Correlated Multimodal Imaging in Life Sciences: Expanding the Biomedical Horizon
  Walter A, Paul-Gilloteaux P, Plochberger B, Sefc L, Verkade P, Mannheim JG, Slezak P, Unterhuber A, Marchetti-Deschmann M, Ogris M, Bühler K, Fixler D, Geyer SH, Weninger WJ, Glösmann M, Handschuh S, Wanek T
  Front. Phys., 09 April 2020 https://doi.org/10.3389/fphy.2020.00047
• Modulating endothelial adhesion and migration impacts stem cell therapies efficacy
  Schäfer R, Schwab M,Siegel G, von Ameln-Mayerhofer A, Buadzec M, Lourhmati A, Wendel H-P, Kluba T, Krueger, M A, Calaminus C, Scheer E, ... Claussen C D, Seifried E, Hermann D M, Northoff H, Danielyan L
  EBioMedicine, Volume 60, 2020, 102987
• DJ-1 (Park7) affects the gut microbiome, metabolites and the development of innate lymphoid cells (ILCs)
  Singh Y, Trautwein C, Dhariwal A, Salker MS, Alauddin Md, Zizmare L, Pelzl L, Feger M, Admard J, Casadei N, Föller M, Pachauri V, Park DS, Mak TW, Frick J-S, Wallwiener D, Brucker SY, Lang F, Riess O
  Sci Rep . 2020 Sep 30;10(1):16131
• Cell motility and migration as determinants of stem cell efficacy
  Danielyan L, Schwab M, Siegel G, ... , Krueger MA, Calaminus C, Naumann U, Winter S, Schaeffeler E, Spogis A, Beer-Hammer S, ... , Hermann DM, Doeppner TR, Seifried E, Gleiter CH, Northoff H, Schäfer R.
  EBioMedicine. 2020 Sep 10;60:102989. Online ahead of print.
• Quo Vadis, Molecular Imaging?
  Grimm J, Kiessling F, Pichler BJ
  J Nucl Med . 2020 Oct;61(10):1428-1434. doi: 10.2967/jnumed.120.241984. Epub 2020 Aug 28
• Comparison of patient stratification by computed tomography radiomics and hypoxia positron emission tomography in head-and-neck cancer radiotherapy
  Socarrás Fernández JA, Mönnich D, Leibfarth S, Welz S, Zwanenburg A, Leger S, Löck S, Pfannenberg C, La Fougère C, Reischl G, Baumann M, Zips D, Thorwarth D
  Phys Imaging Radiat Oncol. 2020 Jul;15:52-59.
• Hydrojet-based delivery of footprint-free iPSC-derived cardiomyocytes into porcine myocardium
  Weber M, Fech A, Jäger L, Steinle H, Bühler L, Perl RM, Martirosian P, Mehling R, Sonanini D, Aicher WK, Nikolaou K, Schlensak C, Enderle MD, Wendel HP, Linzenbold W, Avci-Adali M
  Sci Rep. 2020 Oct 8;10(1):16787. doi: 10.1038/s41598-020-73693-x
• Grassystatin-derived peptides selectively inhibit cathepsin E and have low affinity to cathepsin D
  Stotz S, Bleher D, Kalbacher H, Maurer A
  Biochem Biophys Res Commun. 2020 Jun 18;527(1):238-241. doi: 10.1016/j.bbrc.2020.04.070. Epub 2020 May 1
• Is there a link between very early changes of primary and secondary lymphoid organs in 18 F-FDG-PET/MRI and treatment response to checkpoint inhibitor therapy?
  Seith F, Forschner A, Weide B, Gückel B, Schwartz M, Schwenck J, Othman AE, Fenchel M, Garbe C, Nikolaou K, Schwenzer N, la Fougère C, Pfannenberg C
  J Immunother Cancer. 2020 Aug;8(2):e000656. doi: 10.1136/jitc-2020-000656
• Co-registration of optoacoustic tomography and magnetic resonance imaging data from murine tumour models
  Gehrung M, Tomaszewski M, McIntyre D, Disselhorst J, Bohndiek S
  Photoacoustics. 2020 Jan 16;18:100147. doi: 10.1016/j.pacs.2019.100147
• Advances in the In Vivo Molecular Imaging of Invasive Aspergillosis
  Gunzer M, Thornton CR, Bézière N
  Fungi (Basel). 2020 Dec 4;6(4):338. doi: 10.3390/jof6040338
• Human Dopaminergic Neurons Lacking PINK1 Exhibit Disrupted Dopamine Metabolism Related to Vitamin B6 Co-Factors
  Bus C, Zizmare L, Feldkaemper M, ... , Rapaport D, Ueffing M, Casadei N, Krüger R, Gasser T, Vogt Weisenhorn DM, Kahle
  iScience. 2020 Nov 13;23(12):101797. doi: 10.1016/j.isci.2020.101797
• Non-Invasive Assessment of Hypoxia and Neovascularization with MRI for Identification of Aggressive Breast Cancer
  Bennani-Baiti B, Pinker K, Zimmermann M, Helbich TH, Baltzer PA, Clauser P, Kapetas P, Bago-Horvath Z, Stadlbauer A
  Cancers (Basel). 2020 Jul 24;12(8):2024
• Association between tissue hypoxia, perfusion restrictions, and microvascular architecture alterations with lesion-induced impairment of neurovascular coupling
  Stadlbauer A, Kinfe TM, Zimmermann M, Eyüpoglu I, Brandner N, Buchfelder M, Zaiss M, Dörfler A, Brandner S
  J Cereb Blood Flow Metab. 2020 Aug 12:271678X20947546 doi: 10.1177/0271678X20947546. Epub ahead of print.
• Correlation of C-arm CT acquired parenchymal blood volume (PBV) with 99mTc-macroaggregated albumin (MAA) SPECT/CT for radioembolization work-up
  Weissinger M, Vogel J, Kupferschläger J, Dittmann H, Castaneda Vega SG, Grosse U, Artzner C, Nikolaou K, la Fougere C, Grözinger G.
  PLoS One. 2020 Dec 30;15(12)