2016

2016

• Acetazolamide sensitive tissue calcification and aging of klotho-hypomorphic mice
  Leibrock CB, Alesutan I, Voelkl J, Michael D, Castor T, Kohlhofer U, Quintanilla-Martinez L, Kübler L, Mannheim JG, Pichler BJ, Rosenblatt KP, Kuro-O M, Lang F.
  J Mol Med (Berl). 2016 Jan;94(1):95-106.
• Comprehensive Oncologic Imaging in Infants and Preschool Children With Substantially Reduced Radiation Exposure Using Combined Simultaneous 18F-Fluorodeoxyglucose Positron Emission Tomography/Magnetic Resonance Imaging: A Direct Comparison to 18F-Fluor
  Gatidis S, Schmidt H, Gücke B, Bezrukov I, Seitz G, Ebinger M, Reimold M, Pfannenberg CA, Nikolaou K, Schwenzer NF, Schäfer JF.
  Invest Radiol. 2016 Jan;51(1):7-14.
• [Simultaneous whole-body PET-MRI in pediatric oncology : More than just reducing radiation?].
  Gatidis S, Gückel B, la Fougère C, Schmitt J, Schäfer JF.
  Radiologe. 2016 Jul;56(7):622-30.
• A Nexus Consisting of Beta-Catenin and Stat3 Attenuates BRAF Inhibitor Efficacy and Mediates Acquired Resistance to Vemurafenib.
  Sinnberg T, Makino E, Krueger MA, Velic A, Macek B, Rothbauer U, Groll N6, Pötz O, Czemmel S, Niessner H, Meier F, Ikenberg K, Garbe C, Schittek B.
  EBioMedicine. 2016 Jun;8:132-49.
• A Population-Based Gaussian Mixture Model Incorporating 18F-FDG PET and Diffusion-Weighted MRI Quantifies Tumor Tissue Classes.
  Divine MR, Katiyar P, Kohlhofer U, Quintanilla-Martinez L, Pichler BJ, Disselhorst JA
  J Nucl Med. 2016 Mar;57(3):473-9.
• Combined PET/MRI: from Status Quo to Status Go. Summary Report of the Fifth International Workshop on PET/MR Imaging; February 15-19, 2016; Tübingen, Germany.
  Bailey DL, Pichler BJ, Gückel B, Barthel H, Beer AJ, Botnar R, Gillies R, Goh V, Gotthardt M, Hicks RJ, Lanzenberger R, la Fougere C, Lentschig M, Nekolla SG, Niederdraenk T, Nikolaou K, Nuyts J, Olego D, Riklund KÅ, Signore A, Schäfers M, Sossi V, et al.
  Mol Imaging Biol. 2016 Oct;18(5):637-50.
• Comparison of Positron Emission Tomography Quantification Using Magnetic Resonance- and Computed Tomography-Based Attenuation Correction in Physiological Tissues and Lesions: A Whole-Body Positron Emission Tomography/Magnetic Resonance Study in 66 Patient
  Seith F, Gatidis S, Schmidt H, Bezrukov I, la Fougère C, Nikolaou K, Pfannenberg C, Schwenzer N.
  Invest Radiol. 2016 Jan;51(1):66-71.
• Comparison of small animal CT contrast agents
  Mannheim JG, Schlichthaerle T, Kuebler L, Quintanilla-Martinez L, Kohlhofer U, Kneilling M, Pichler BJ
  Contrast Media Mol Imaging. 2016 Jul;11(4):272-84.
• Comparison of Tumor Uptake Heterogeneity Characterization Between Static and Parametric 18F-FDG PET Images in Non-Small Cell Lung Cancer
  Tixier F, Vriens D, Cheze-Le Rest C, Hatt M, Disselhorst JA, Oyen WJ, de Geus-Oei LF, Visser EP, Visvikis D.
  J Nucl Med. 2016 Jul;57(7):1033-9.
• Correlation between positron emission tomography and Cerenkov luminescence imaging in vivo and ex vivo using 64Cu-labeled antibodies in a neuroblastoma mouse model.
  Maier FC, Schmitt J, Maurer A, Ehrlichmann W, Reischl G, Nikolaou K, Handgretinger R, Pichler BJ, Thaiss WM.
  Oncotarget. 2016 Oct 11;7(41):67403-67411
• CXCR1 Regulates Pulmonary Anti-Pseudomonas Host Defense.
  Carevic M, Öz H, Fuchs K, Laval J, Schroth C, Frey N, Hector A, Bilich T, Haug M, Schmidt A, Autenrieth SE, Bucher K, Beer-Hammer S, Gaggar A, Kneilling M, Benarafa C, Gao JL, Murphy PM, Schwarz S, Moepps B, Hartl D.
  J Innate Immun. 2016;8(4):362-73
• Decoding intratumoral heterogeneity of breast cancer by multiparametric in vivo imaging: A translational study.
  Schmitz J, Schwab J, Schwenck J, Chen Q, Quintanilla-Martinez L, Hahn M, Wietek B, Schwenzer N, Staebler A, Kohlhofer U, Aina OH, Hubbard NE, Reischl G, Borowsky AD, Brucker S, Nikolaou K, La Fougère C, Cardiff RD, Pichler BJ, Schmid AM
  Cancer Res. 2016 Sep 15;76(18):5512-22.
• Enhanced binding of necrosis-targeting immunocytokine NHS-IL12 after local tumor irradiationin murine xenograft models.
  Eckert F, Schmitt J, Zips D, Krueger MA, Pichler BJ, Gillies SD, Strittmatter W, Handgretinger R, Schilbach K
  Cancer Immunol Immunother. 2016 Aug;65(8):1003-13.
• Fluorescence and Cerenkov luminescence imaging. Applications in small animal research.
  Schwenck J, Fuchs K, Eilenberger SH, Rolle AM, Castaneda Vega S, Thaiss WM, Maier FC.
  Nuklearmedizin. 2016;55(2):63-70.
• ImmunoPET/MR imaging allows specific detection of Aspergillus fumigatus lung infection in vivo
  Rolle AM, Hasenberg M, Thornton CR, Solouk-Saran D, Männ L, Weski J, Maurer A, Fischer E, Spycher PR, Schibli R, Boschetti F, Stegemann-Koniszewski S, Bruder D, Severin GW, Autenrieth SE, Krappmann S, Davies G, Pichler BJ, Gunzer M, Wiehr S.
  Proc Natl Acad Sci U S A. 2016 Feb 23;113(8):E1026-33
• In Vivo Evaluation of [11C]DASB for Quantitative SERT Imaging in Rats and Mice
  Walker M, Ehrlichmann W, Stahlschmidt A, Pichler B, Fischer K.
  J Nucl Med. 2016 Jan;57(1):115-21.
• Necrotic Cell Sensor Clec4e Promotes a Pro-Atherogenic Macrophage Phenotype Through Activation of the Unfolded Protein Response
  Clément M, Basatemur G, Masters L, Baker L, Bruneval P, Iwawaki T, Kneilling M, Yamasaki S, Goodall J, Mallat Z
  Circulation. 2016 Oct 4;134(14):1039-1051
• New pathogen-specific immunoPET/MR tracer for molecular imaging of a systemic bacterial infection
  Wiehr S, Warnke P, Rolle AM, Schütz M, Oberhettinger P, Kohlhofer U, Quintanilla-Martinez L, Maurer A, Thornton C, Boschetti F, Reischl G, Autenrieth IB, Pichler BJ, Autenrieth SE
  Oncotarget. 2016 Mar 8;7(10):10990-1001.
• PI3K pathway inhibition achieves potent antitumor activity in melanoma brain metastases in vitro and in vivo.
  Niessner H, Schmitz J, Tabatabai G, Schmid A, Calaminus C, Sinnberg T, Weide B, Eigentler TK, Garbe C, Schittek B, Quintanilla-Fend L, Bender B, Mai M, Praetorius C, Beissert S, Schackert G,..., Pichler BJ,...,Meier F
  Clin Cancer Res. 2016 Dec 1;22(23):5818-5828
• PI3K-resistant GSK3 controls adiponectin formation and protects from metabolic syndrome.
  Chen H; Fajol A; Hoene M; Zhang B; Schleicher ED; Lin Y; Calaminus C; Pichler BJ; Weigert C; Haring HU; Lang F; Foller, M
  Proc Natl Acad Sci U S A. 2016 May 17;113(20):5754-9.
• Preclinical evaluation of the anti-tumor effects of the natural isoflavone genistein in two xenograft mouse models monitored by [18F]FDG, [18F]FLT, and [64Cu]NODAGA-cetuximab small animal PET.
  Honndorf VS, Wiehr S, Rolle AM, Schmitt J, Kreft L, Quintanilla-Martinez L, Kohlhofer U, Reischl G, Maurer A, Boldt K, Schwarz M, Schmidt H, Pichler BJ
  Oncotarget. 2016 May 10;7(19):28247-61.
• The emerging role of myeloid-derived suppressor cells in lung diseases.
  Kolahian S, Öz HH, Zhou B, Griessinger CM, Rieber N, Hartl D.
  Eur Respir J. 2016 Mar;47(3):967-77.
• The Synergistic Effect of Selumetinib/Docetaxel Combination Therapy Monitored by [(18)F]FDG/[(18)F]FLT PET and Diffusion-Weighted Magnetic Resonance Imaging in a Colorectal Tumor Xenograft Model.
  Honndorf VS, Schmidt H, Wiehr S, Wehrl HF, Quintanilla-Martinez L, Stahlschmidt A, Barjat H, Emmas SA, Pichler BJ
  Mol Imaging Biol. 2016 Apr;18(2):249-57.
• The Positron Emission Tomography Tracer 3'-Deoxy-3'-[18F]Fluorothymidine ([18F]FLT) Is Not Suitable to Detect Tissue Proliferation Induced by Systemic Yersinia enterocolitica Infection in Mice
  Wiehr S, Rolle AM, Warnke P, Kohlhofer U, Quintanilla-Martinez L, Reischl G, Autenrieth IB, Pichler BJ, Autenrieth SE
  PLoS One. 2016 Oct 4;11(10):e0164163.
• [18F]Fluoro-azomycin-2´-deoxy-β-d-ribofuranoside - A new imaging agent for tumor hypoxia in comparison with [18F]FAZA
  Schweifer A, Maier F, Ehrlichmann W, Lamparter D, Kneilling M, Pichler BJ, Hammerschmidt F, Reischl G
  Nucl Med Biol. 2016 Dec;43(12):759-769
• Structural and molecular myelination deficits occur prior to neuronal loss in the YAC128 and BACHD models of Huntington disease
  Teo RT, Hong X, Yu-Taeger L, Huang Y, Tan LJ, Xie Y, To XV, Guo L, Rajendran R, Novati A, Calaminus C, Riess O, Hayden MR, Nguyen HP, Chuang KH, Pouladi MA
  Hum Mol Genet. 2016 Jul 1;25(13):2621-2632
• First protein and peptide characterization of the tarsal adhesive secretions in the desert locust, Schistocerca gregaria, and the Madagascar hissing cockroach, Gromphadorhina portentosa
  Betz O, Maurer A, Verheyden AN, Schmitt C, Kowalik T, Braun J, Grunwald I, Hartwig A, Neuenfeldt M
  2016 Oct;25(5):541-9
• Symbiotic gut commensal bacteria act as host cathepsin S activity regulators
  Steimle A, Gronbach K, Beifuss B, Schäfer A, Harmening R, Bender A, Maerz JK, Lange A, Michaelis L, Maurer A, Menz S, McCoy K, Autenrieth IB, Kalbacher H, Frick JS
  J Autoimmun. 2016 Dec;75:82-95
• Improved selectivity of mIBG uptake into neuroblastoma cells in vitro and in vivo by inhibition of organic cation transporter 3 uptake using clinically approved corticosteroids
  Bayer M, Schmitt J, Dittmann H, Handgretinger R, Bruchelt G, Sauter AW
  Nucl Med Biol. 2016 Sep;43(9):543-51