2024

2024

• Open-source flow setup for rapid and efficient [18 F]fluoride drying for automation of PET tracer syntheses.
  Menzel F, Cotton J, Ziegler T, Maurer A, Neumaier JM.
  J Labelled Comp Radiopharm. 2024 Feb;67(2):40-58.
• Augmenting MEK inhibitor efficacy in BRAF wild-type melanoma: synergistic effects of disulfiram combination therapy.
  Meraz-Torres F, Niessner H, Plöger S, Riel S, Schörg B, Casadei N, Kneilling M, Schaller M, Flatz L, Macek B, Eigentler T, Rieß O, Garbe C, Amaral T, Sinnberg T.
  J Exp Clin Cancer Res. 2024 Jan 23;43(1):30.
• Histological and functional characterization of 3D human skin models mimicking the inflammatory skin diseases psoriasis and atopic dermatitis.
  Scheurer J, Sauer B, Focken J, Giampetraglia M, Jäger A, Schürch CM, Weigelin B, Schittek B.
  Dis Model Mech. 2024 Jan 1;17(1):dmm050541.
• A novel approach to guide GD2-targeted therapy in pediatric tumors by PET and [64Cu]Cu-NOTA-ch14.18/CHO.
  Trautwein NF, Schwenck J, Seitz C, Seith F, Calderón E, von Beschwitz S, Singer S, Reischl G, Handgretinger R, Schäfer J, Lang P, Pichler BJ, Schulte JH, la Fougère C, Dittmann H.
  Theranostics. 2024 Jan 20;14(3):1212-1223.
• [18F]pFBC, a Covalent CLIP-Tag Radiotracer for Detection of Viral Reporter Gene Transfer in the Murine Brain.
  Bowden GD, Stotz S, Dunkel G, Haas S, Kimmerle E, Schaller M, Weigelin B, Herfert K, Pichler BJ, Maurer A.
  Bioconjug Chem. 2024 Feb 21;35(2):254-264.
• Image-guided metabolomics and transcriptomics reveal tumour heterogeneity in luminal A and B human breast cancer beyond glucose tracer uptake.
  Yang Q, Deng S, Preibsch H, Schade TC, Koch A, Berezhnoy G, Zizmare L, Fischer A, Gückel B, Staebler A, Hartkopf AD, Pichler BJ, la Fougère C, Hahn M, Bonzheim I, Nikolaou K, Trautwein C.
  Clin Transl Med. 2024 Feb;14(2):e1550.
• Basic principles of artificial intelligence in dermatology explained using melanoma.
  Hartmann T, Passauer J, Hartmann J, Schmidberger L, Kneilling M, Volc S.
  J Dtsch Dermatol Ges. 2024 Mar;22(3):339-347.
• Quantitative Metabolomics and Lipoprotein Analysis of PDAC Patients Suggests Serum Marker Categories for Pancreatic Function, Pancreatectomy, Cancer Metabolism, and Systemic Disturbances.
  Bae G, Berezhnoy G, Flores A, Cannet C, Schäfer H, Dahlke MH, Michl P, Löffler MW, Königsrainer A, Trautwein C.
  J Proteome Res. 2024 Apr 5;23(4):1249-1262.
• Immunocytokines with target cell-restricted IL-15 activity for treatment of B cell malignancies.
  Zekri L, Hagelstein I, Märklin M, Klimovich B, Christie M, Lindner C, Kämereit S, Prakash N, Müller S, Stotz S, Maurer A, Greve C, Schmied B, Atar D, Rammensee HG, Jung G, Salih HR.
  Sci Transl Med. 2024 Mar 6;16(737):eadh1988.
• Presenilin-1 mutation position influences amyloidosis, small vessel disease, and dementia with disease stage.
  Joseph-Mathurin N, Feldman RL, Lu R, Shirzadi Z, ... , Reischl G, ... , Benzinger TLS; Dominantly Inherited Alzheimer Network.
  Alzheimers Dement. 2024 Apr;20(4):2680-2697.
• Multi-tracer PET correlation analysis reveals disease-specific patterns in Parkinson's disease and asymptomatic LRRK2 pathogenic variant carriers compared to healthy controls.
  Mannheim JG, Fu JF, Wegener T, Klyuzhin IS, Vafai N, Shahinfard E, McKenzie J, Strongosky A, Wszolek ZK, Jon Stoessl A, Sossi V.
  Neuroimage Clin. 2024;42:103600.
• A 5:2 intermittent fasting regimen ameliorates NASH and fibrosis and blunts HCC development via hepatic PPARα and PCK1.
  Gallage S, Ali A, Barragan Avila JE, ..., Joerke V, Zizmare L, ... , Machauer T, Pichler B, Malek NP, Longerich T, Roth S, Rose AJ, Schwenck J, Trautwein C, Karimi MM, Heikenwalder M.
  Cell Metab. 2024 Jun 4;36(6):1371-1393.e7.
• CD19-immunoPET for noninvasive visualization of CD19 expression in B-cell lymphoma patients.
  Sonanini D, Schwenck J, Blaess S, Schmitt J, Maurer A, Ehrlichmann W, Ritter M, Skokowa J, Kneilling M, Jung G, Fend F, Krost S, Seitz CM, Lang P, Reischl G, Handgretinger R, Fougère C, Pichler BJ.
  Biomark Res. 2024 May 12;12(1):50.
• Metabolic fingerprinting by nuclear magnetic resonance of hepatocellular carcinoma cells during p53 reactivation-induced senescence.
  Knopf P, Pacheco-Torres J, Zizmare L, Mori N, Wildes F, Zhou B, Krishnamachary B, Mironchik Y, Kneilling M, Trautwein C, Pichler BJ, Bhujwalla ZM.
  NMR Biomed. 2024 Apr 8:e5157.
• Innexin hemichannel activation by Microplitis bicoloratus ecSOD monopolymer reduces ROS.
  Meng JH, Huang YB, Long J, Cai QC, Qiao X, Zhang QL, Zhang LD, Yan X, Jing R, Liu XS, Zhou SJ, Yuan YS, Yin-Chen Ma, Zhou LX, Peng NN, Li XC, Cai CH, Tang HM, Martins AF, Jiang JX, Kai-Jun Luo.
  iScience. 2024 Mar 18;27(4):109469.
• Development of High-Throughput Experimentation Approaches for Rapid Radiochemical Exploration.
  Webb EW, Cheng K, Winton WP, Klein BJC, Bowden GD, Horikawa M, Liu SW, Wright JS, Verhoog S, Kalyani D, Wismer M, Krska SW, Sanford MS, Scott PJH.
  J Am Chem Soc. 2024 Apr 17;146(15):10581-10590.
• Western diet increases brain metabolism and adaptive immune responses in a mouse model of amyloidosis.
  Poxleitner M, Hoffmann SHL, Berezhnoy G, Ionescu TM, Gonzalez-Menendez I, Maier FC, Seyfried D, Ehrlichmann W, Quintanilla-Martinez L, Schmid AM, Reischl G, Trautwein C, Maurer A, Pichler BJ, Herfert K, Beziere N.
  J Neuroinflammation. 2024 May 14;21(1):129.
• Optimization and impact of sensitivity mode on abbreviated scan protocols with population-based input function for parametric imaging of [18F]-FDG for a long axial FOV PET scanner.
  Lan W, Sari H, Rominger A, Fougère C, Schmidt FP.
  Eur J Nucl Med Mol Imaging. 2024 May 20.
• Retinal metabolism displays evidence for uncoupling of glycolysis and oxidative phosphorylation via Cori-, Cahill-, and mini-Krebs-cycle.
  Chen Y, Zizmare L, Calbiague V, Wang L, Yu S, Herberg FW, Schmachtenberg O, Paquet-Durand F, Trautwein C.
  Elife. 2024 May 13;12:RP91141.
• Targeting Gαi2 in neutrophils protects from myocardial ischemia reperfusion injury.
  Köhler D, Leiss V, Beichert L, Killinger S, Grothe D, Kushwaha R, Schröter A, Roslan A, Eggstein C, Focken J, Granja T, Devanathan V, Schittek B, Lukowski R, Weigelin B, Rosenberger P, Nürnberg B, Beer-Hammer S.
  Basic Res Cardiol. 2024 May 30.
• Advancing Parkinson's Disease Diagnostics: The Potential of Arylpyrazolethiazole Derivatives for Imaging α-Synuclein Aggregates.
  Bonanno F, Saw RS, Bleher D, Papadopoulos I, Bowden GD, Bjerregaard-Andersen K, Windhorst AD, Pichler BJ, Herfert K, Maurer A.
  ACS Omega. 2024 May 30;9(23):24774-24788.
• KCa channel targeting impairs DNA repair and invasiveness of patient-derived glioblastoma stem cells in culture and orthotopic mouse xenografts which only in part is predictable by KCa expression levels.
  Ganser K, Stransky N, Abed T, Quintanilla-Martinez L, Gonzalez-Menendez I, Naumann U, Koch P, Krueger M, Ruth P, Huber SM, Eckert F.
  Int J Cancer. 2024 Jun 27.
• Optimizing SUV Analysis: A Multicenter Study on Preclinical FDG-PET/CT Highlights the Impact of Standardization.
  Kuntner C, Alcaide C, Anestis D, Bankstahl JP, Boutin H, Brasse D, Elvas F, Forster D, Rouchota MG, Tavares A, Teuter M, Wanek T, Zachhuber L, Mannheim JG.
  Mol Imaging Biol. 2024 Jun 21.